2,4-di-O-methyl-D-xylose | 911659-79-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,4-di-O-methyl-D-xylose
• 英文别名: O²,O⁴-dimethyl-β-D-xylopyranose；(2R,3R,4S,5R)-3,5-dimethoxyoxane-2,4-diol
• CAS: 911659-79-5
• 化学式: C₇H₁₄O₅
• 分子量: 178.185
• InChiKey: HZLKARALBVQSKO-XZBKPIIZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  68.2
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  (1R,2S,4S,5'R,6S,7S,8R,9S,12S,13S,15R,16R,18S)-16-[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R)-4-[(2S,4S,5S)-2,5-dimethoxy-4-[(2S,3R,4R,5S,6S)-3,4,5-trimethoxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,5-dimethoxyoxan-2-yl]oxy-3,5-dimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-15-ol 生成 2,4-di-O-methyl-D-xylose
  参考文献：
  名称：

  KISHOR, NAVIN;SATI, O. P., J. NATUR. PROD., 53,(1990) N, C. 1557-1559

  摘要：

  DOI：

文献信息

• Cariniferosides A–F and other steroidal biglycosides from the starfish Asteropsis carinifera
  作者：Timofey V. Malyarenko、Alla A. Kicha、Natalia V. Ivanchina、Anatoly I. Kalinovsky、Pavel S. Dmitrenok、Svetlana P. Ermakova、Valentin A. Stonik

  DOI：10.1016/j.steroids.2011.06.006

  日期：2011.11

  Six new steroidal biglycosides, cariniferosides A-F (1-6), were isolated along with six previously known glycosides, 7-12, from the alcoholic extract of the starfish Asteropsis carinifera. The structures of 1-6 were determined by extensive NMR and ESIMS techniques. The isolated compounds did not show any apparent cytotoxicity in cancer cell lines HCT-116, RPMI-7951, and T-47D, but sulfated compounds 6,11, and 12 demonstrated a significant inhibition of RPMI-7951 and T-47D cell colony formation in a soft agar clonogenic assay. (C) 2011 Elsevier Inc. All rights reserved.