Hithiol | 39322-47-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Hithiol
• 英文别名: (2R)-2-amino-3-sulfanylpropanoic acid;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
• CAS: 39322-47-9
• 化学式: C9H19NO8S
• 分子量: 301.32
• InChiKey: GVEITDPWYKNDNJ-LGDQNDJISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.05
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  183
• 氢给体数：
  8
• 氢受体数：
  10

文献信息

• Method for inhibiting or reversing non-enzymatic glycation
  申请人：Szwergold Benjamin

  公开号：US20080009547A1

  公开（公告）日：2008-01-10

  The present invention relates to a method for inhibiting or reversing non-enzymatic glycation of the first intermediate of a biological moiety using an α-thiolamine. By inhibiting or reversing non-enzymatic glycation of the biological moiety, conditions such as aging and diabetic complications can be prevented or reversed.

  本发明涉及使用α-硫代胺抑制或逆转生物分子的第一中间体的非酶促糖基化的方法。通过抑制或逆转生物分子的非酶促糖基化，可以预防或逆转衰老和糖尿病并发症等疾病。
• Methods Of Preparing Thiazolidines
  申请人：Nagasawa Herbert T.

  公开号：US20110184185A1

  公开（公告）日：2011-07-28

  The present invention provides methods of preparing thiazolidines, and in particular methods of preparing ribose-cysteine.

  本发明提供了制备噻唑啉类化合物的方法，特别是制备核糖-半胱氨酸的方法。
• RNA CONTAINING COENZYMES, BIOTIN, OR FLUOROPHORES, AND METHODS FOR THEIR PREPARATION AND USE
  申请人：UNIVERSITY OF SOUTHERN MISSISSIPPI

  公开号：US20040241649A1

  公开（公告）日：2004-12-02

  Materials and methods for incorporating adenosine derivatives into the 5′ end of transcribed RNA are disclosed. Adenosine derivatives include naturally occurring compounds such as Coenzyme A, NAD, and FAD, as well as various non-naturally occurring compounds. The derivatives can be used to impart desirable properties to the RNA such as fluorescence, the ability to bind to receptors or ligands, and improved catalytic activity. The transcribed RNAs can be used in a variety of applications including nucleic acid detection, designed or random generation of catalytic RNAs, antisense applications, and in the study of RNA structure and function

  公开了将腺苷衍生物并入转录RNA 5'端的材料和方法。腺苷衍生物包括天然化合物，如辅酶A，NAD和FAD，以及各种非自然发生的化合物。这些衍生物可用于赋予RNA所需的性质，如荧光，与受体或配体结合的能力以及改善催化活性。转录的RNA可用于各种应用，包括核酸检测，设计或随机生成催化RNA，反义应用以及用于研究RNA结构和功能。
• COMPOSITIONS COMPRISING SUGAR-CYSTEINE PRODUCTS
  申请人：Nagasawa Herbert T.

  公开号：US20140348811A1

  公开（公告）日：2014-11-27

  The present invention provides compositions comprising sugar, cysteine, and/or sugar-cysteine products, methods of preparing the same, and/or using the same.

  本发明提供了包含糖、半胱氨酸和/或糖半胱氨酸产物的组合物，其制备方法和/或使用方法。
• Glycoconjugate vaccines
  申请人：London School of Hygiene and Tropical Medicine

  公开号：US10039814B2

  公开（公告）日：2018-08-07

  The disclosure relates to a glycoconjugate vaccine conferring protection against Francisella tularensis infections and a method to manufacture a glycoconjugate antigen.

  本公开涉及一种可预防土拉弗氏菌感染的糖结合疫苗，以及一种制造糖结合抗原的方法。