2-[2-(Hydroxymethoxy)ethoxy]ethan-1-ol--propane-1,2-diol (1/1) | 845306-79-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-(Hydroxymethoxy)ethoxy]ethan-1-ol--propane-1,2-diol (1/1)
• 英文别名: 2-[2-(hydroxymethoxy)ethoxy]ethanol;propane-1,2-diol
• CAS: 845306-79-8
• 化学式: C8H20O6
• 分子量: 212.24
• InChiKey: AWVGFPDMWHQABR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.68
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• PREPARATIONS OF HYDROPHOBIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE AND USE THEREOF
  申请人：NICOX OPHTHALMICS, INC.

  公开号：US20190169224A1

  公开（公告）日：2019-06-06

  The present invention further provides method of preparing nanocrystals of a hydrophobic therapeutic agent such as fluticasone or triamcinolone, pharmaceutical compositions (e.g., topical or intranasal compositions) thereof and methods for treating and/or preventing the signs and/or symptoms of disorders such as blepharitis, meibomian gland dysfunction or skin inflammation or a respiratory disease (e.g., asthma).