1-[2-(2-Ethoxy-ethoxy)-ethoxy]-propane | 18854-42-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-[2-(2-Ethoxy-ethoxy)-ethoxy]-propane
• 英文别名: 1-[2-(2-Ethoxyethoxy)ethoxy]propane
• CAS: 18854-42-7
• 化学式: C₉H₂₀O₃
• 分子量: 176.256
• InChiKey: PXQCQQARRAYIFS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• CONJUGATE OF A PHOTOSENSITISER AND CHITOSAN AND USES THEREOF
  申请人：PCI BIOTECH AS

  公开号：US20150202293A1

  公开（公告）日：2015-07-23

  The present invention relates to novel chitosan-based conjugates, e.g. nanocarriers, comprising a derivative of the biocompatible polymer chitosan conjugated to a photosensitising agent, and uses thereof in photochemical internalisation (PCI) and photodynamic therapy (PDT). The invention also relates to the use of the novel conjugates of the invention in treatment or prevention of diseases, particularly cancer, and for vaccination purposes.

  本发明涉及新型基于壳聚糖的共轭物，例如纳米载体，包括生物相容性聚合物壳聚糖的衍生物与光敏剂结合，以及它们在光化学内部化（PCI）和光动力疗法（PDT）中的用途。该发明还涉及本发明的新型共轭物在治疗或预防疾病，特别是癌症以及用于疫苗目的的用途。
• Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof
  申请人：Westfälische Wilhelms-Universität Münster

  公开号：EP2644601A1

  公开（公告）日：2013-10-02

  The present invention relates to the field of therapeutic, diagnostic and imaging agents and more specifically to compounds having the following general formula. The compounds are inhibitors of matrix-metalloproteinases (MMPs).

  本发明涉及治疗、诊断和成像剂领域，更具体地涉及具有以下一般式的化合物。这些化合物是基质金属蛋白酶（MMPs）的抑制剂。
• NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION
  申请人：Su Zhuang

  公开号：US20130303438A1

  公开（公告）日：2013-11-14

  The present invention relates to a compound of the formula (I): or pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same, a method for treating or preventing a viral infection using the same.

  本发明涉及公式（I）的化合物或其药学上可接受的盐，其中符号如规范中所定义; 包含相同化合物的制药组合物，使用相同化合物治疗或预防病毒感染的方法。
• NOVEL SYNTHETIC PROCEDURE AND CANCER TREATMENT WITH CISPLATIN DERIVATIVES
  申请人：Spangelo Bryan L.

  公开号：US20130225546A1

  公开（公告）日：2013-08-29

  A method of reducing the in vivo viability of cancer cells selected from the group consisting of breast cancer cells, lung cancer cells, prostate cancer cells and melanoma cancer cells has steps of: a) identifying a prospective patient having cancer cells selected from the group consisting of breast cancer cells, lung cancer cells, prostate cancer cells and melanoma cancer cells; and b) administering a cisplatin derivative to the prospective patient so that the cisplatin derivative will contact the cancer cells; wherein the cisplatin derivative is a 4,4′-bis[RO]-2,2′-bipyridine)PtCl 2 where, R is selected from the group consisting of —(CH 2 ) n CH3 where n=2, 3, 4 or 5, and —(CH 2 ) n [O(CH 2 ) m ] y O(CH 2 ) z CH 3 where n=2, m=2, y=2, z=1. A novel synthetic process for the manufacture of these compounds (and their analogs) is also provided.

  一种减少乳腺癌细胞、肺癌细胞、前列腺癌细胞和黑色素瘤癌细胞在体内存活能力的方法，包括以下步骤：a) 识别患有乳腺癌细胞、肺癌细胞、前列腺癌细胞和黑色素瘤癌细胞中的一种或多种的潜在患者；和b) 向潜在患者给予顺铂衍生物，使顺铂衍生物接触到癌细胞；其中，顺铂衍生物是4,4'-双[RO]-2,2'-联吡啶)PtCl2，其中，R选自—(CH2)nCH3（其中n=2、3、4或5）和—( )n[O( )m]yO( )zCH3（其中n=2、m=2、y=2、z=1）的群体中。同时提供一种制造这些化合物（及其类似物）的新型合成方法。
• Agent and method for removing rosin-base solder flux
  申请人：ARAKAWA CHEMICAL INDUSTRIES, LTD.

  公开号：EP0464652A1

  公开（公告）日：1992-01-08

  The invention provides a cleaning agent for removal of a rosin-base solder flux, the cleaning agent comprising a mixture of (A) at least one glycol ether compound of the formula (1) wherein R¹ is a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, R² is an alkyl group having 1 to 5 carbon atoms, R³ is a hydrogen atom or a methyl group and k is an integer of 2 to 4, (B) at least one nonionic surfactant, (C) at least one phosphate anionic surfactant, and also provides a cleaning method for removing a rosin-base solder flux, the method comprising bringing the above cleaning agent into contact with the rosin-base solder flux.

  本发明提供了一种用于去除松香基焊剂的清洗剂，该清洗剂包括以下物质的混合物 (A) 至少一种式(1)的乙二醇醚化合物 其中 R¹ 是氢原子或具有 1 至 5 个碳原子的烷基，R² 是具有 1 至 5 个碳原子的烷基，R³ 是氢原子或甲基，k 是 2 至 4 的整数、 (B) 至少一种非离子表面活性剂、 (C) 至少一种磷酸盐阴离子表面活性剂，还提供了一种去除松香基焊剂的清洗方法，该方法包括使上述清洗剂与松香基焊剂接触。