4-[(1-甲基-4(1H)-吡啶亚基)亚乙基]-2,5-环己二烯-1-酮水合物 | 123333-69-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-[(1-甲基-4(1H)-吡啶亚基)亚乙基]-2,5-环己二烯-1-酮水合物
• 英文名称: Merocyanine
• 英文别名: 4-[(1-Methyl-4(1H)-pyridinylidene)ethylidene]-2,5-cyclohexadien-1-one hydrate；4-[2-(1-methylpyridin-4-ylidene)ethylidene]cyclohexa-2,5-dien-1-one;hydrate
• CAS: 123333-69-7
• 化学式: C₁₄H₁₃NO*H₂O
• 分子量: 229.279
• InChiKey: YVYPWIIOYSHDAT-UHFFFAOYSA-N

物化性质

• 熔点：
  233-238 °C(lit.)

计算性质

• 辛醇/水分配系数(LogP)：
  1.68
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38

文献信息

• ARRAY FOR RAPID DETECTION OF A MICROORGANISM
  申请人：KIMBERLY-CLARK WORLDWIDE, INC.

  公开号：EP2057275B1

  公开（公告）日：2017-02-01
• METHOD FOR DETECTING CANDIDA ON SKIN
  申请人：KIMBERLY-CLARK WORLDWIDE, INC.

  公开号：EP2056890B1

  公开（公告）日：2015-11-18
• RAPID ASSESSMENT OF UPPER RESPIRATORY CONDITIONS
  申请人：KIMBERLY-CLARK WORLDWIDE, INC.

  公开号：EP2195655A1

  公开（公告）日：2010-06-16
• Method for detecting Candida on skin
  申请人：Martin Stephanie

  公开号：US20080057532A1

  公开（公告）日：2008-03-06

  A method and system for rapidly detecting Candida on the skin of a host, such as an infant with diaper rash, is provided. The method includes contacting a dermal sample with a colorant that exhibits a certain spectral response (e.g., color change) in the presence of Candida . For example, the colorant may change from a first color to a second color, from colorless to a color, or from a color to colorless. The colorant is typically capable of differentiating between Candida (e.g., Candida albicans ) and other microorganisms commonly associated with diaper rash, such as S. aureus and E. coli . Thus, when a dermal sample is placed into contact with the colorant, the color change may simply be observed to determine whether the infection is caused by Candida . If the color change occurs to a certain extent (e.g., from yellow to bright red), it may be determined that the test sample contains Candida . Likewise, if a color change occurs to a lesser extent (e.g., from yellow to faint orange) or not at all, it may be determined that the dermal sample contains other microorganisms (e.g., S. aureus or E. coli ), no infection is present, or that the infection is simply due to other causes. Regardless, it will become readily apparent whether or not treatment for Candida is needed.
• Array for rapid detection of a microorganism
  申请人：Martin Stephanie M.

  公开号：US20080057533A1

  公开（公告）日：2008-03-06

  A method for detecting a microorganism or class of microorganisms is provided. More specifically, the method employs an array that contains a plurality of discrete regions (referred to as “addresses”) spaced apart on a solid support in a predetermined pattern. The addresses are selected so that the array provides a distinct spectral response (e.g., pattern of colors) or “fingerprint” for a particular microorganism or class of microorganisms. For example, the array may provide a certain spectral response in the presence of one microorganism or class of microorganisms (e.g., gram-negative bacteria), but provide a completely different spectral response in the presence of another microorganism or class of microorganisms (e.g., gram-positive bacteria). Detection of the spectral response provided by the array may thus allow for differentiation between microorganisms.