(E)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-phenyl-1-(1,2,4-triazol-1-yl)but-3-en-2-ol | 1159001-53-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (E)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-phenyl-1-(1,2,4-triazol-1-yl)but-3-en-2-ol
• CAS: 1159001-53-2
• 化学式: C₂₄H₁₉Cl₂N₃O₂
• 分子量: 452.34
• InChiKey: DESHCFCTPNSAMZ-OUKQBFOZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  31
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  60.2
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (E)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-phenyl-1-(1,2,4-triazol-1-yl)but-3-en-2-ol 、 3-溴丙炔 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 5.5h， 以490 mg的产率得到1-[(E)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-phenyl-2-prop-2-ynoxy-but-3-enyl]-1,2,4-triazole
  参考文献：
  名称：

  [EN] FUNGICIDAL SUBSTITUTED 1-{2-[2-HALO-4-(4-HALOGEN-PHENOXY)-PHENYL ]-2-ALKOXY-2-CYCLYL-ETHYL}-1H [1,2,4]TRIAZOLE COMPOUNDS
  [FR] COMPOSÉS DE 1-{2-[2-HALOGÉNO-4-(4-HALOGÉNO-PHÉNOXY)-PHÉNYL]-2-ALCOXY-2-CYCLYL-ÉTHYL}-1H-[1,2,4]TRIAZOLE SUBSTITUÉS FONGICIDES

  摘要：

  本发明涉及以下化学式I所定义的取代的1-{2-[2-卤代-4-(4-卤代苯氧基)苯基]-2-烷氧基-2-环丙基乙基}-1H-[1,2,4]三唑化合物及其N-氧化物和盐，以及制备这些化合物的过程和中间体，还涉及至少包含一种这样的化合物的组合物。本发明还涉及使用这样的化合物和组合物来对抗有害真菌和至少包含一种这样的化合物的种子包衣。

  公开号：

  WO2013024080A1

文献信息

• [EN] FUNGICIDAL ALKYL-SUBSTITUTED 2-[2-CHLORO-4-(4-CHLORO-PHENOXY)-PHENYL]-1-[1,2,4]TRIAZOL-1-YL-ETHANOL COMPOUNDS<br/>[FR] COMPOSÉS FONGICIDES DE 2-[2-CHLORO-4-(4-CHLORO-PHÉNOXY)-PHÉNYL]-1-[1,2,4]TRIAZOL-1-YL-ÉTHANOL SUBSTITUÉ PAR ALKYLE
  申请人：BASF SE

  公开号：WO2013010862A1

  公开（公告）日：2013-01-24

  The present invention relates to the use of alkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds of formula I as defined in the description, and the N-oxides, and salts thereof for combating harmful fungi and seed coated with at least one such compound. The invention also relates to novel alkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds, processes and intermediates for preparing these compounds and also to compositions comprising at least one such compound.

  本发明涉及将公式I中定义的烷基取代的2-[2-氯-4-(4-氯苯氧基)-苯基]-1-[1,2,4]三唑-1-基乙醇化合物以及其N-氧化物和盐用于对抗有害真菌和至少包含一种这种化合物的种子。该发明还涉及新颖的烷基取代的2-[2-氯-4-(4-氯苯氧基)-苯基]-1-[1,2,4]三唑-1-基乙醇化合物，用于制备这些化合物的工艺和中间体，以及包含至少一种这种化合物的组合物。
• [EN] FUNGICIDAL PHENYLALKYL-SUBSTITUTED 2-[2-CHLORO-4-(4-CHLORO-PHENOXY)-PHENYL]-1-[1,2,4]TRIAZOL-1-YL-ETHANOL COMPOUNDS<br/>[FR] COMPOSÉS FONGICIDES DE 2-[2-CHLORO-4-(4-CHLOROPHÉNOXY)PHÉNYL]-1- [1,2,4]TRIAZOL-1-YL-ÉTHANOL SUBSTITUÉS PAR UN PHÉNYLALKYLE
  申请人：BASF SE

  公开号：WO2013010894A1

  公开（公告）日：2013-01-24

  The present invention relates to phenylalkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1 -[1,2,4]triazol-1-yl-ethanol compounds of formula I as defined in the description, and the N-oxides, and salts thereof, their preparation and intermediates for preparing them. The invention also relates to the use of these compounds for combating harmful fungi and seed coated with at least one such compound and also to compositions comprising at least one such compound.

  本发明涉及公式I中定义的苯基烷基取代的2-[2-氯-4-(4-氯苯氧)-苯基]-1-[1,2,4]三唑-1-基乙醇化合物，以及其N-氧化物和盐，它们的制备和制备中间体。本发明还涉及使用这些化合物对抗有害真菌以及至少包含一种这样的化合物的种子涂层，以及包含至少一种这样的化合物的组合物。
• Fungicidal substituted 1--1H-[1,2,4]triazole compounds
  申请人：Dietz Jochen

  公开号：US20140187422A1

  公开（公告）日：2014-07-03

  The present invention relates to substituted 1-2-[2-halo-4-(4-halogen-phenoxy)-phenyl]-2-alkoxy-2-cyclyl-ethyl}-1H-[1,2,4]triazole compounds of formula I as defined in the description, and the N-oxides, and salts thereof, processes and intermediates for preparing these compounds and also to compositions comprising at least one such compound. The invention also relates to the use of such compounds and compositions for combating harmful fungi and seed coated with at least one such compound.

  本发明涉及一种代替的1-2-[2-卤代-4-(4-卤代苯氧基)苯基]-2-烷氧基-2-环烷基乙基}-1H-[1,2,4]三唑化合物，其化学式如描述中所定义，以及其N-氧化物和盐，制备这些化合物的过程和中间体，以及包含至少一种这样的化合物的组合物。本发明还涉及使用这样的化合物和组合物来对抗有害真菌和至少包含一种这样的化合物的种子涂层。
• Fungicidal Alkyl-Substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol Compounds
  申请人：Dietz Jochen

  公开号：US20140128255A1

  公开（公告）日：2014-05-08

  The present invention relates to the use of alkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds of formula I as defined in the description, and the N-oxides, and salts thereof for combating harmful fungi and seed coated with at least one such compound. The invention also relates to novel alkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds, processes and intermediates for preparing these compounds and also to compositions comprising at least one such compound.

  本发明涉及使用式I中定义的烷基取代的2-[2-氯-4-(4-氯苯氧基)-苯基]-1-[1,2,4]三唑-1-基乙醇化合物及其N-氧化物和盐来对抗有害真菌和至少包被有一种这样的化合物的种子。本发明还涉及新的烷基取代的2-[2-氯-4-(4-氯苯氧基)-苯基]-1-[1,2,4]三唑-1-基乙醇化合物、制备这些化合物的过程和中间体，以及包含至少一种这样的化合物的组合物。
• Substituted [1,2,4] Triazole Compounds
  申请人：BASF SE

  公开号：US20150313229A1

  公开（公告）日：2015-11-05

  The present invention relates to substituted [1,2,4]triazol compounds of the formula I wherein the substituents are defined in the claims and the description, and the N-oxides and the salts thereof for combating phytopathogenic fungi, and to the use and methods for combating phytopathogenic fungi and to seeds coated with at least one such compound. The invention also relates to processes for preparing these compounds, intermediates, processes for preparing such intermediates, and to compositions comprising at least one compound I.

  本发明涉及式I的取代[1,2,4]三唑化合物，其中取代基在权利要求和说明中被定义，以及其N-氧化物和盐，用于防治植物病原真菌，以及用于防治植物病原真菌的方法和使用至少一种该化合物包裹的种子。该发明还涉及制备这些化合物的过程，中间体，制备这种中间体的过程，以及包含至少一种I化合物的组合物。