(2R,4R,5R,6R)-6-((R)-1,2-Dimethoxy-ethyl)-4,5-dimethoxy-2-((2R,3R,4R,5R,7R)-2,3,4,5,7-pentamethoxy-7-methoxycarbonyl-heptyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester | 121275-90-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,4R,5R,6R)-6-((R)-1,2-Dimethoxy-ethyl)-4,5-dimethoxy-2-((2R,3R,4R,5R,7R)-2,3,4,5,7-pentamethoxy-7-methoxycarbonyl-heptyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester
• CAS: 121275-90-9
• 化学式: C₂₇H₅₀O₁₅
• 分子量: 614.685
• InChiKey: KXTCJNQTXKCDEE-DDIXEZJCSA-N

反应信息

• 作为反应物：
  描述：

  (2R,4R,5R,6R)-6-((R)-1,2-Dimethoxy-ethyl)-4,5-dimethoxy-2-((2R,3R,4R,5R,7R)-2,3,4,5,7-pentamethoxy-7-methoxycarbonyl-heptyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 (2R,4R,5R,6R,7R)-8-[(2R,4R,5R,6R)-6-((R)-1,2-Dimethoxy-ethyl)-2-hydroxymethyl-4,5-dimethoxy-tetrahydro-pyran-2-yloxy]-2,4,5,6,7-pentamethoxy-octan-1-ol
  参考文献：
  名称：

  GLC-MS of reduced, acetylated, and methylated (2 → 4)- and (2 → 8)-linked disaccharides of 3-deoxy-pD-manno-octulopyranosonic acid (Kdo)

  摘要：

  Synthetic alpha- and beta-(2 --> 4)- and alpha- and beta-(2 --> 8)-linked disaccharides of 3-deoxy-D-manno-octulopyranosonic acid (Kdo), of which the synthesis of the beta-(2 --> 4)-linked compound is described here, were used to develop a simple GLC-MS method for the determination of their anomeric configuration. The GLC and GLC-MS data for the reduced and acetylated or methylated derivatives of the above compounds indicate the a-linked synthetic disaccharides to be identical to those.isolated from bacterial lipopolysaccharides.

  DOI：

  10.1016/0008-6215(92)84008-g