[2-[Acetyl-[7-[acetyl(2,2-diphosphonoethyl)amino]heptyl]amino]-1-phosphonoethyl]phosphonic acid | 1104610-58-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: [2-[Acetyl-[7-[acetyl(2,2-diphosphonoethyl)amino]heptyl]amino]-1-phosphonoethyl]phosphonic acid
• CAS: 1104610-58-3
• 化学式: C₁₅H₃₄N₂O₁₄P₄
• 分子量: 590.335
• InChiKey: KFYUXKCOOYWLTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.8
• 重原子数：
  35
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  271
• 氢给体数：
  8
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  [2-[Acetyl-[7-[acetyl(2,2-diphosphonoethyl)amino]heptyl]amino]-1-phosphonoethyl]phosphonic acid 、 在 硫酸 作用下， 以 aq. buffer 为溶剂， 反应 24.0h， 生成
  参考文献：
  名称：

  A screening method of uranyl extractants in H2SO4 solutions

  摘要：

  A UV-Vis spectrophotometric and colorimetric screening method was developed for the selection of powerful and selective ligands for the uranyl ion in sulfuric acid media. The coordinating properties of a series of molecules (mono and bisphosphonate) toward UO22+ were examined through ligand displacement reactions observed by UV-visible from the {ArzH(4)-UO2}(2-) reference complex where Na(2)ArzH(6) is a chromogenic molecule displaying a strong affinity for uranium. Uranium/iron selectivity was evaluated by recovering the screening data from two independent sets of experiments using two different chromogenic chelates: arsenazo III for uranium(VI) and BrPADAP for iron(III). As a result, two bisphosphonate ligands among a set of more than 50 phosphonate molecules were found to display a good affinity for UO22+ and relevant U/Fe selectivity at pH = 2.1. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.11.068