2-{2H,3H-thieno[3,4-b][1,4]dioxin-2-yl}acetic acid | 882513-47-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-{2H,3H-thieno[3,4-b][1,4]dioxin-2-yl}acetic acid
• 英文别名: 2-(2,3-dihydrothieno[3,4-b][1,4]dioxin-3-yl)acetic acid
• CAS: 882513-47-5
• 化学式: C₈H₈O₄S
• 分子量: 200.21
• InChiKey: SQIMSGSVPIZLBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  84
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] INTEGRATED ZWITTERIONIC CONJUGATED POLYMERS FOR BIOELECTRONICS, BIOSENSING, REGENERATIVE MEDICINE, AND ENERGY APPLICATIONS<br/>[FR] POLYMÈRES CONJUGUÉS ZWITTERIONIQUES INTÉGRÉS POUR APPLICATIONS DE BIOÉLECTRONIQUE, BIODÉTECTION, MÉDECINE RÉGÉNÉRATRICE ET ÉNERGIE
  申请人：CHENG GANG

  公开号：WO2015054484A1

  公开（公告）日：2015-04-16

  The present invention is directed to a versatile and high performance zwitterionic CP platform, which integrates all desired functions into one material. This zwitterionic CP consists of the conducting backbone and multifunctional zwitterionic side chains. Non-conducting zwitterionic materials gain electronic conductivity through the conducting backbone and CPs obtain excellent biocompatibility, sensitivity to environmental stimuli and controllable antifouling properties via multifunctional zwitterionic side chains. Unique properties from two distinct materials (conducting materials and zwitterionic materials) are integrated into one material without sacrificing any properties. This platform can potentially be adapted for a range of applications (e.g. bioelectronics, tissue engineering, wound healing, robotic prostheses, biofuel cell, etc.), which all require high performance conducting materials with excellent antifouling/biocompatibility at complex biointerfaces. This conducting material platform will significantly advance the development of conducting polymers in the field of biomedicine and biotechnology.

  本发明涉及一种多功能高性能的带正负离子的聚合物平台，将所有所需功能集成到一个材料中。这种带正负离子的聚合物由导电骨架和多功能带正负离子侧链组成。非导电的带正负离子材料通过导电骨架获得电子导电性，而聚合物通过多功能带正负离子侧链获得优异的生物相容性、对环境刺激的敏感性和可控的防污染性质。两种不同材料（导电材料和带正负离子材料）的独特性能被集成到一个材料中，而不会牺牲任何性能。这种平台可以潜在地适用于一系列应用（例如生物电子学、组织工程、伤口愈合、机器人假肢、生物燃料电池等），这些应用都需要具有优异的防污染/生物相容性的高性能导电材料在复杂的生物界面上。这种导电材料平台将显著推进导电聚合物在生物医学和生物技术领域的发展。
• INTEGRATED ZWITTERIONIC CONJUGATED POLYMERS FOR BIOELECTRONICS, BIOSENSING, REGENERATIVE MEDICINE, AND ENERGY APPLICATIONS
  申请人：THE UNIVERSITY OF AKRON

  公开号：US20160244554A1

  公开（公告）日：2016-08-25

  The present invention is directed to a versatile and high performance zwitterionic CP platform, which integrates all desired functions into one material. This zwitterionic CP consists of the conducting backbone and multifunctional zwitterionic side chains. Non-conducting zwitterionic materials gain electronic conductivity through the conducting backbone and CPs obtain excellent biocompatibility, sensitivity to environmental stimuli and controllable antifouling properties via multifunctional zwitterionic side chains. Unique properties from two distinct materials (conducting materials and zwitterionic materials) are integrated into one material without sacrificing any properties. This platform can potentially be adapted for a range of applications (e.g. bioelectronics, tissue engineering, wound healing, robotic prostheses, biofuel cell, etc.), which all require high performance conducting materials with excellent antifouling/biocompatibility at complex biointerfaces. This conducting material platform will significantly advance the development of conducting polymers in the field of biomedicine and biotechnology.

  本发明涉及一种多功能高性能的带正负电离的聚合物平台，将所有所需功能集成到一个材料中。这种带正负电离的聚合物由导电骨架和多功能带正负电离的侧链组成。非导电的带正负电离材料通过导电骨架获得电子导电性，聚合物通过多功能带正负电离的侧链获得优异的生物相容性、对环境刺激的敏感性和可控的抗污染性能。两种不同材料（导电材料和带正负电离材料）的独特性能被整合到一个材料中，而不会牺牲任何性能。这种平台可能适用于一系列应用（例如生物电子学、组织工程、伤口愈合、机器人假肢、生物燃料电池等），这些应用都需要具有优异的抗污染/生物相容性的高性能导电材料在复杂的生物界面上。这种导电材料平台将显著推进导电聚合物在生物医学和生物技术领域的发展。
• Integrated zwitterionic conjugated polymers for bioelectronics, biosensing, regenerative medicine, and energy applications
  申请人：THE UNIVERSITY OF AKRON

  公开号：US10407537B2

  公开（公告）日：2019-09-10

  The present invention is directed to a versatile and high performance zwitterionic CP platform, which integrates all desired functions into one material. This zwitterionic CP consists of the conducting backbone and multifunctional zwitterionic side chains. Non-conducting zwitterionic materials gain electronic conductivity through the conducting backbone and CPs obtain excellent biocompatibility, sensitivity to environmental stimuli and controllable antifouling properties via multifunctional zwitterionic side chains. Unique properties from two distinct materials (conducting materials and zwitterionic materials) are integrated into one material without sacrificing any properties. This platform can potentially be adapted for a range of applications (e.g. bioelectronics, tissue engineering, wound healing, robotic prostheses, biofuel cell, etc.), which all require high performance conducting materials with excellent antifouling/biocompatibility at complex biointerfaces. This conducting material platform will significantly advance the development of conducting polymers in the field of biomedicine and biotechnology.

  本发明涉及一种多功能、高性能的齐聚物平台，它将所有所需的功能集成到一种材料中。这种齐聚物由导电骨架和多功能齐聚物侧链组成。非传导性齐聚物通过导电骨架获得电子传导性，而氯化石蜡则通过多功能齐聚物侧链获得优异的生物相容性、对环境刺激的敏感性和可控的防污特性。两种不同材料（导电材料和齐聚物）的独特性能被整合到一种材料中，而不会牺牲任何性能。该平台可用于一系列应用（如生物电子学、组织工程、伤口愈合、机器人假肢、生物燃料电池等），这些应用都需要在复杂的生物界面上具有优异抗污性/生物相容性的高性能导电材料。这一导电材料平台将大大推动生物医学和生物技术领域导电聚合物的发展。
• US9695275B2
  申请人：——

  公开号：US9695275B2

  公开（公告）日：2017-07-04