3-ethyl-2,6-diphenylpiperidin-4-one semicarbazone | 201335-61-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 3-ethyl-2,6-diphenylpiperidin-4-one semicarbazone
• 英文别名: [(3-ethyl-2,6-diphenylpiperidin-4-ylidene)amino]urea
• CAS: 201335-61-7
• 化学式: C₂₀H₂₄N₄O
• 分子量: 336.437
• InChiKey: IQTQOKWGAZZQNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.51
• 重原子数：
  25.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  79.51
• 氢给体数：
  3.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  3-ethyl-2,6-diphenylpiperidin-4-one semicarbazone 在 quinolinium flurochromate 作用下， 反应 0.33h， 以90%的产率得到3-乙基-2,6-二苯基-4-哌啶酮
  参考文献：
  名称：

  Microwave Assisted Deprotection of Heterocyclic Semicarbazones by Quinolinium Flurochromate

  摘要：

  在微波照射下，利用蒙脱石K10粘土，奎啉铬酸盐（QFC）从2,6-二苯基哌啶-4-酮半卡巴宗（PPS）及其在3、3和5位替代的烷基衍生物再生半卡巴宗，形成酮，并且产率良好。

  DOI：

  10.14233/ajchem.2017.20786
• 作为产物：
  描述：

  3-乙基-2,6-二苯基-4-哌啶酮 、 盐酸氨基脲 在 sodium acetate 作用下， 以 甲醇 为溶剂， 反应 4.0h， 以75%的产率得到3-ethyl-2,6-diphenylpiperidin-4-one semicarbazone
  参考文献：
  名称：

  5,7-二芳基哌啶[3,4-D]硒/噻二唑的合成

  摘要：

  摘要 标题化合物 5,7-二芳基哌啶基[3,4-d]硒二酰胺 (III) & 5,7-二芳基哌啶基[3,4-d]噻二唑 (IV) 由 4-哌啶酮的缩氨基脲衍生物环化制备。 (II) 用二氧化硒和亚硫酰氯。分别。产物的形成由光谱数据证实。

  DOI：

  10.1080/10426509708043502

文献信息

• Vimala; Jani Bai, Asian Journal of Chemistry, 2010, vol. 22, # 7, p. 5705 - 5710
  作者：Vimala、Jani Bai

  DOI：——

  日期：——
• STUDY OF CORROSION INHIBITION PROPERTIES OF NOVEL SEMICARBAZONES ON MILD STEEL IN ACIDIC SOLUTIONS
  作者：RATHIKA GOVINDASAMY、SWETHA AYAPPAN

  DOI：10.4067/s0717-97072015000100004

  日期：——

  The inhibition efficiency of corrosion on mild steel using acids by three different novel Semicarbazones as inhibitors have been studied using weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy methods. The inhibition efficiency, corrosion rate, the nature of anchoring sites and the adsorption characteristics have been determined from the results. It was found that the newly synthesized compounds behaved as mixed type inhibitors with high inhibition efficiency. The inhibition efficiency increases with increasing the inhibitors concentration but decreases with increasing the temperature. Addition of halide ion enhances the inhibition efficiency. The adsorption of the inhibitors on the mild steel surface obey Langmuir adsorption isotherm. Scanning Electron Spectroscopy is used to examine the surface morphology of mild steel samples both in the presence and absence of inhibitors at optimum conditions. Scanning Electron Microscope reveals the formation of a smooth, dense protective layer in the presence of inhibitor.