(2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-chloro-tetrahydro-pyran-2-carboxylic acid methyl ester | 902464-49-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-chloro-tetrahydro-pyran-2-carboxylic acid methyl ester
• CAS: 902464-49-7
• 化学式: C₃₅H₄₇ClN₂O₂₁
• 分子量: 867.212
• InChiKey: NUMBEDVELQADTK-SZTHHPMMSA-N

反应信息

• 作为反应物：
  描述：

  (2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-chloro-tetrahydro-pyran-2-carboxylic acid methyl ester 在 sodium hydroxide 、 sodium methylate 、 silver salicylate 、 臭氧 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Design and Synthesis of b-Series Ganglioside Mimetics

  摘要：

  Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD3 and GQlb, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.

  DOI：

  10.1055/s-1997-3259
• 作为产物：
  描述：

  乙酰氯 、 (2S,4S,5R,6R)-5-Acetylamino-6-{(S)-[(2R,6S,8R,9R,10S)-9-acetylamino-10-hydroxy-5-oxo-8-((1R,2R)-1,2,3-trihydroxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-hydroxy-methyl}-2,4-dihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester 以 甲醇 、 溶剂黄146 为溶剂， 生成 (2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-chloro-tetrahydro-pyran-2-carboxylic acid methyl ester
  参考文献：
  名称：

  Design and Synthesis of b-Series Ganglioside Mimetics

  摘要：

  Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD3 and GQlb, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.

  DOI：

  10.1055/s-1997-3259