| 194997-78-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 194997-78-9
• 化学式: C₂₄H₄₇BrNiP₂Si₃
• 分子量: 620.435
• InChiKey: OKUXZUVNYULUQY-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  、 3-Brom-propin-(1)-yl-(1)-lithium 以 乙醚 为溶剂， 生成
  参考文献：
  名称：

  Nickel-mediated synthesis of dialkynyl and trialkynyl ethenes — demetallation reactions

  摘要：

  Metalorganic syntheses of the title compounds starting from l-alkynes and Ni(cod)(PMe3)(2) or Ni(PM3)(4) consist of less than six steps and afford better than 50% overall yields of isolated compounds. Elimination of the metal by reductive C,C coupling in diorganonickel complexes under 1 bar CO and workup in aqueous hydrochloric acid are the key steps in the preparation af(RC=C)R'C=C(R) (C=CR) (R=SiMe3, CMe3; R'=H, CH3, C6H5, C=CH, C=CCH3, C=CCMe3, C=CSiMe3, C=CSiPh3, C=CC6H5, C=CC6H4F, C=CC6H11, C=CCH2SiMe3). Starting from 3-bromopropyne the initial C,C-coupling reaction is followed by an oxidative addition of the CH,Br function to zerovalent nickel and a second C,C coupling, which generates the tetradecadienetetrayne skeleton of (RC=C)(R)C=(RC=C)C-C=C-CH2-CH2-C=C-(RC=C)C=C(C=CR)-(R) (R=SiMe3).

  DOI：

  10.1016/s0020-1693(97)05485-6