4-(1-苯并呋喃-2-基)苯甲醛 | 53348-90-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: 4-(1-苯并呋喃-2-基)苯甲醛
• 英文名称: 4-(2-Oxoindolin-5-YL)benzaldehyde
• 英文别名: 4-(2-oxo-1,3-dihydroindol-5-yl)benzaldehyde
• CAS: 53348-90-6
• 化学式: C₁₅H₁₁NO₂
• 分子量: 237.25
• InChiKey: CHDRKGBEBLDLRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2932999099

文献信息

• [EN] THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF<br/>[FR] COMPOSÉS THÉRAPEUTIQUES ET LEURS PROCÉDÉS D'UTILISATION
  申请人：AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR

  公开号：WO2021061053A1

  公开（公告）日：2021-04-01

  There are provided new heterobifunctional agents designed to mediated formation of protein-protein dimers and promote ubiqutination of a protein of the dimer. Also provided are methods of synthesizing the agents, pharmaceutical formulations including the agents, and methods of using the agents to treat, ameliorate or cure diseases characterized by protein over-expression or malfunction. In various embodiments, the present disclosure relates to a compound of Formula (I) or a pharmaceutically acceptable salt, solvate, stereoisomer or prodrug thereof.