(7-chloro-indolizin-3-yl)-(4-fluoro-phenyl)-methanone | 675139-37-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (7-chloro-indolizin-3-yl)-(4-fluoro-phenyl)-methanone
• 英文别名: (7-Chloroindolizin-3-yl)-(4-fluorophenyl)methanone
• CAS: 675139-37-4
• 化学式: C₁₅H₉ClFNO
• 分子量: 273.694
• InChiKey: FIYZGJYDHAETDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  21.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Synthesis of indolizines
  申请人：Synta Pharmaceuticals Corp.

  公开号：US20040152897A1

  公开（公告）日：2004-08-05

  Disclosed are methods of preparing substituted indolizines represented by the following formula: 1 comprising reacting a substrate represented by the following formula: 2 with either the cyclization reagent of the following formula: 3 or, a reagent prepared by reacting the compound represented the formula below with an alkylating agent: 4 The variables in the above formulas are defined herein.