5,6-Dihydro-indol-4,7-dion | 24536-12-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5,6-Dihydro-indol-4,7-dion
• 英文别名: 5,6-dihydro-indole-4,7-dione；5,6-dihydro-1H-indole-4,7-dione
• CAS: 24536-12-7
• 化学式: C₈H₇NO₂
• mdl: MFCD19219425
• 分子量: 149.149
• InChiKey: XPYPGUZLSZTBMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  49.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• IL-6 inhibitors and methods of treatment
  申请人：University of Florida Research Foundation, Incorporated

  公开号：US11530181B2

  公开（公告）日：2022-12-20

  The instant invention describes compounds having IL-6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by IL-6.

  本发明描述了具有 IL-6 调节活性的化合物，以及治疗由 IL-6 介导的疾病、失调或症状的方法。
• IL-6 INHIBITORS AND METHODS OF TREATMENT
  申请人：University of Florida Research Foundation, Incorporated

  公开号：US20210206718A1

  公开（公告）日：2021-07-08

  The instant invention describes compounds having IL-6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by IL-6.
• [EN] IL-6 INHIBITORS AND METHODS OF TREATMENT<br/>[FR] INHIBITEURS DE IL-6 ET MÉTHODES DE TRAITEMENT
  申请人：UNIV FLORIDA

  公开号：WO2019165158A1

  公开（公告）日：2019-08-29

  The instant invention describes compounds having IL-6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by IL-6.