3-methyl-1-methylsulfanyl-butan-2-one | 39199-24-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-methyl-1-methylsulfanyl-butan-2-one
• 英文别名: 3-Methyl-1-methylsulfanylbutan-2-one
• CAS: 39199-24-1
• 化学式: C₆H₁₂OS
• 分子量: 132.227
• InChiKey: QJAOLHMWVCFERT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Broad Spectrum Beta-Lactamase Inhibitors
  申请人：Gladius Pharmaceuticals Corporation

  公开号：US20170327515A1

  公开（公告）日：2017-11-16

  Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.
• US9809605B1
  申请人：——

  公开号：US9809605B1

  公开（公告）日：2017-11-07