[Problem to be Solved]
It is intended to obtain a hollow fiber membrane for blood processing that has high membrane performance, can reduce leak misdetection, is excellent in antioxidative performance and blood compatibility, carries a low risk of hydrophilic polymer elution or a leak from hollow fibers, is easy to prime, and has highly stable permeability in a harsh environment.
[Solution]
The present invention provides a hollow fiber membrane for blood processing, containing a hydrophilic polymer, a polysulfone-based resin, and a fat-soluble vitamin, wherein
a content A of the hydrophilic polymer, which is a mass ratio of the hydrophilic polymer to a total mass of the hydrophilic polymer and the polysulfone-based resin in a whole of the hollow fiber membrane for blood processing, is 3% by mass or larger and 10% by mass or smaller,
an abundance ratio B of the hydrophilic polymer, which is a mass ratio of the hydrophilic polymer to the total mass of the hydrophilic polymer and the polysulfone-based resin in an inner surface of the hollow fiber membrane for blood processing, is 35% by mass or larger and 50% by mass or smaller, and
an abundance of the fat-soluble vitamin in an entire surface of the hollow fiber membrane for blood processing is 0.5 mg or larger and 25 mg or smaller based on 1 g of the hollow fiber membrane.
[有待解决的问题]
旨在获得一种用于血液处理的中空纤维膜,该膜具有较高的膜性能,可减少泄漏误检,抗氧化性能和血液相容性优异,亲
水性聚合物洗脱或中空纤维泄漏的风险较低,易于填料,并且在恶劣环境中具有高度稳定的渗透性。
[解决方案]
本发明提供了一种用于血液处理的中空纤维膜,它含有亲
水性聚合物、聚砜基
树脂和脂溶性
维生素,其中
亲
水性聚合物的含量 A,即亲
水性聚合物与血液处理用中空纤维膜整体中亲
水性聚合物和聚砜基
树脂总质量的质量比,大于等于 3%,小于等于 10%、
亲
水性聚合物的丰度比 B(即血液处理用中空纤维膜内表面中亲
水性聚合物与亲
水性聚合物和聚砜基
树脂总质量的质量比)为 35% (以质量为单位)或更大,50% (以质量为单位)或更小,以及
以 1 克中空纤维膜为基准,血液处理用中空纤维膜整个表面中脂溶性
维生素的丰度为 0.5 毫克或更大,25 毫克或更小。