6-[2,5-Dibromo-4-[6-(trimethylazaniumyl)hexoxy]phenoxy]hexyl-trimethylazanium | 1380645-29-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 6-[2,5-Dibromo-4-[6-(trimethylazaniumyl)hexoxy]phenoxy]hexyl-trimethylazanium
• 英文别名: 6-[2,5-dibromo-4-[6-(trimethylazaniumyl)hexoxy]phenoxy]hexyl-trimethylazanium
• CAS: 1380645-29-3
• 化学式: C₂₄H₄₄Br₂N₂O₂
• 分子量: 552.434
• InChiKey: QHEIXBKRKPGVIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  30
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,4-dibromo-2,5-bis((6-bromohexyl)oxy)benzene 、 三甲胺 以 四氢呋喃 、 水 为溶剂， 反应 48.5h， 以93%的产率得到6-[2,5-Dibromo-4-[6-(trimethylazaniumyl)hexoxy]phenoxy]hexyl-trimethylazanium
  参考文献：
  名称：

  Water-soluble poly(p-phenylene) incorporating methoxyphenol units: Highly sensitive and selective chemodosimeters for hypochlorite

  摘要：

  A series of water-soluble poly(p-phenylene)s (PPPs), named N-PPPx (x = 10, 25 and 50), were directly synthesized by Suzuki coupling in aqueous solution. The structures of the polymers were characterized by H-1 NMR and elemental analysis. The polymers exhibit similar absorption and emission spectra with three absorption maxima at ca. 205, 290 and 350 nm, and emission maximum at 420 nm in phosphate buffer saline (PBS) solution. Upon addition of hypochlorite. N-PPPx shows a decrease of absorption band at ca. 350 nm and a fluorescent quenching. Compared to their model compound PMOPP, N-PPPx shows a significantly amplified fluorescent quenching. Moreover, the K-sv is decreased with the increasing content of methoxyphenol moieties in N-PPPx. In view of the sensitivity and selectivity, N-PPP10 and N-PPP25 are very promising polymeric fluorescent probes to hypochlorite under the aqueous condition. (C) 2012 Published by Elsevier Ltd.

  DOI：

  10.1016/j.polymer.2012.03.063