(4-fluoro-phenyl)-(7-methoxy-indolizin-3-yl)-methanone | 675139-36-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4-fluoro-phenyl)-(7-methoxy-indolizin-3-yl)-methanone
• 英文别名: (4-Fluorophenyl)-(7-methoxyindolizin-3-yl)methanone
• CAS: 675139-36-3
• 化学式: C₁₆H₁₂FNO₂
• 分子量: 269.275
• InChiKey: SQJIIJZMUPENJL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• SYNTHESIS OF INDOLIZINES
  申请人：Synta Pharmaceuticals Corporation

  公开号：EP1537105A2

  公开（公告）日：2005-06-08
• Synthesis of indolizines
  申请人：Synta Pharmaceuticals Corp.

  公开号：US20040152897A1

  公开（公告）日：2004-08-05

  Disclosed are methods of preparing substituted indolizines represented by the following formula: 1 comprising reacting a substrate represented by the following formula: 2 with either the cyclization reagent of the following formula: 3 or, a reagent prepared by reacting the compound represented the formula below with an alkylating agent: 4 The variables in the above formulas are defined herein.
• [EN] SYNTHESIS OF INDOLIZINES<br/>[FR] SYNTHESE D'INDOLIZINES
  申请人：SYNTA PHARMACEUTICALS CORP

  公开号：WO2004024727A2

  公开（公告）日：2004-03-25

  Disclosed are methods of preparing substituted indolizines represented by the following formula: comprising reacting a substrate represented by the following formula: with either the cyclization reagent of the following formula: or, a reagent prepared by reacting the compound represented the formula below with an alkylating agent: The variables in the above formulas are defined herein.