n-butyl 2-phenylimidazole-5-carboxylate | 1369937-09-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: n-butyl 2-phenylimidazole-5-carboxylate
• CAS: 1369937-09-6
• 化学式: C₁₄H₁₆N₂O₂
• 分子量: 244.293
• InChiKey: ZLNHZMFWJNCKJP-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 以94%的产率得到n-butyl 2-phenylimidazole-5-carboxylate
  参考文献：
  名称：

  Highly efficient oxidation of 2-imidazoline-5-carboxylic derivatives to imidazole-5-carboxylic derivatives by dioxygen

  摘要：

  A highly efficient and environmental-benign oxidation by dioxygen (or air) as the sole oxidant was first applied for the conversion of 2-imidazoline-5-carboxylic derivatives to imidazole-5-carboxylic derivatives in very good and excellent yields. The substituent effect on 2-imidazoline ring was investigated. This protocol was also suitable for the synthesis of 2-imidazoles in relatively large scale. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.01.025