2-[2-(12-Sulfanyldodecoxy)ethoxy]ethanol | 1174656-59-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-(12-Sulfanyldodecoxy)ethoxy]ethanol
• 英文别名: 2-[2-(12-sulfanyldodecoxy)ethoxy]ethanol
• CAS: 1174656-59-7
• 化学式: C₁₆H₃₄O₃S
• 分子量: 306.51
• InChiKey: RFKFRTXFFJEQAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  20
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  39.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-[2-(12-Sulfanyldodecoxy)ethoxy]ethanol 、 三苯基氯甲烷 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 以84%的产率得到2-(2-((12-(tritylthio)dodecyl)oxy)ethoxy)ethan-1-ol
  参考文献：
  名称：

  Synthesis of phosphorylcholine–oligoethylene glycol–alkane thiols and their suppressive effect on non-specific adsorption of proteins

  摘要：

  A series of hosphorylcholine-oligoethylene glycol-alkane thiols were synthesized, and their suppressive effect on the non-specific adsorption of proteins was evaluated by comparison with corresponding oligoethylene glycol-alkane thiols. it was found that phosphorylcholine-oligoethylene glycol-alkane thiols had a greater suppressive effect on the non-specific adsorption of proteins. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.04.091
• 作为产物：
  描述：

  2-(2-((12-(tritylthio)dodecyl)oxy)ethoxy)ethan-1-ol 在 三乙基硅烷 作用下， 以 二氯甲烷 、 三氟乙酸 为溶剂， 反应 0.5h， 以90%的产率得到2-[2-(12-Sulfanyldodecoxy)ethoxy]ethanol
  参考文献：
  名称：

  Synthesis of phosphorylcholine–oligoethylene glycol–alkane thiols and their suppressive effect on non-specific adsorption of proteins

  摘要：

  A series of hosphorylcholine-oligoethylene glycol-alkane thiols were synthesized, and their suppressive effect on the non-specific adsorption of proteins was evaluated by comparison with corresponding oligoethylene glycol-alkane thiols. it was found that phosphorylcholine-oligoethylene glycol-alkane thiols had a greater suppressive effect on the non-specific adsorption of proteins. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.04.091

文献信息

• Synthesis of phosphorylcholine–oligoethylene glycol–alkane thiols and their suppressive effect on non-specific adsorption of proteins
  作者：Mutsuo Tanaka、Takahiro Sawaguchi、Yukari Sato、Kyoko Yoshioka、Osamu Niwa

  DOI：10.1016/j.tetlet.2009.04.091

  日期：2009.7

  A series of hosphorylcholine-oligoethylene glycol-alkane thiols were synthesized, and their suppressive effect on the non-specific adsorption of proteins was evaluated by comparison with corresponding oligoethylene glycol-alkane thiols. it was found that phosphorylcholine-oligoethylene glycol-alkane thiols had a greater suppressive effect on the non-specific adsorption of proteins. (C) 2009 Elsevier Ltd. All rights reserved.