2-hydroxy-β-(pyrid-3-yl)-propiophenone | 98696-89-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-hydroxy-β-(pyrid-3-yl)-propiophenone
• 英文别名: 1-(2-hydroxyphenyl)-3-(pyridin-3-yl)propan-1-one；1-(2-Hydroxyphenyl)-3-pyridin-3-ylpropan-1-one
• CAS: 98696-89-0
• 化学式: C₁₄H₁₃NO₂
• 分子量: 227.263
• InChiKey: ILCNQXDENPRLMT-UHFFFAOYSA-N

物化性质

• 沸点：
  408.8±30.0 °C(Predicted)
• 密度：
  1.197±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  50.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• FLAVOR MOLECULES
  申请人：Daniher Andrew

  公开号：US20100040753A1

  公开（公告）日：2010-02-18

  A method of providing a range of flavors to an orally-receivable or ingestible product, the method including adding at least one compound, including salts thereof, of the formula: wherein R 1 may be H, OH, O(CH 2 ) 2 OH, OCH 2 OCH 3 or R 2 may be selected from a range of 5- and 6-membered heterocyclic rings, and wherein R 3 may be H or OH. The compounds give rise to a wide range of flavors, and some are useful as sweetness enhancers, this allowing sweetener content to be reduced while maintaining sweetness. Also disclosed are orally-receivable or ingestible products including the compounds.

  一种为口腔可接受或可摄入产品提供一系列口味的方法，该方法包括添加至少一种化合物，其包括以下式子的盐：其中R1可以是H，OH，O（CH2）2OH，O OCH3或R2可以从5-和6-成员杂环环中选择，其中R3可以是H或OH。这些化合物产生广泛的口味，其中一些化合物可用作甜味增强剂，从而可以减少甜味剂含量而保持甜味。还公开了包含这些化合物的口腔可接受或可摄入产品。
• Flavor Molecules
  申请人：DANIHER Andrew

  公开号：US20100272656A1

  公开（公告）日：2010-10-28

  A method of providing a range of flavors to an orally-receivable or ingestible product, the method including adding at least one compound, including salts thereof, of the formula: wherein R 1 may be H, OH, O(CH 2) 2 OH, OCH 2 OCH 3 or R 2 may be selected from a range of 5- and 6-membered heterocyclic rings, and wherein R 3 may be H or OH. The compounds give rise to a wide range of flavors, and some are useful as sweetness enhancers, this allowing sweetener content to be reduced while maintaining sweetness. Also disclosed are orally-receivable or ingestible products including the compounds.

  一种为口服或摄入产品提供一系列口味的方法，该方法包括添加至少一种化合物，其包括上述公式中的盐：其中R1可以是H、OH、O(CH2)2OH、O OCH3或；R2可以从5-和6-成员杂环环中选择，其中R3可以是H或OH。这些化合物产生广泛的口味，其中一些有助于增强甜味，从而可以在保持甜味的同时减少甜味剂含量。此外，还披露了包括这些化合物的口服或摄入产品。
• Chemosensory Receptor Ligand-Based Therapies
  申请人：Baron Alain D.

  公开号：US20130281387A1

  公开（公告）日：2013-10-24

  Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
• US8449936B2
  申请人：——

  公开号：US8449936B2

  公开（公告）日：2013-05-28
• US8715761B2
  申请人：——

  公开号：US8715761B2

  公开（公告）日：2014-05-06