azidomethyl α-D-mannopyranosyl-(1→6)-[α-D-mannopyranosyl-(1→3)]-α-D-mannopyranosyl-(1→6)-[α-D-mannopyranosyl-(1→3)]-1-thio-β-D-mannopyranoside | 1574535-78-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: azidomethyl α-D-mannopyranosyl-(1→6)-[α-D-mannopyranosyl-(1→3)]-α-D-mannopyranosyl-(1→6)-[α-D-mannopyranosyl-(1→3)]-1-thio-β-D-mannopyranoside
• CAS: 1574535-78-6
• 化学式: C₃₁H₅₃N₃O₂₅S
• 分子量: 899.833
• InChiKey: QIHNZFPGVHJYLN-DTJBZYHLSA-N

反应信息

• 作为产物：
  描述：

  azidomethyl 2-O-acetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1→6)-[2-O-acetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1→3)]-2,4-di-O-benzoyl-α-D-mannopyranosyl-(1→6)-[2-Oacetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1→3)]-2,4-di-Obenzoyl-1-thio-β-D-mannopyranoside 在 氘代甲醇 、 sodium methoxide-d3 作用下， 反应 20.0h， 以71%的产率得到azidomethyl α-D-mannopyranosyl-(1→6)-[α-D-mannopyranosyl-(1→3)]-α-D-mannopyranosyl-(1→6)-[α-D-mannopyranosyl-(1→3)]-1-thio-β-D-mannopyranoside
  参考文献：
  名称：

  Synthesis of high-mannose 1-thio glycans and their conjugation to protein

  摘要：

  高甘露醣结构的Mannosylthiol衍生物Man9GlcNAc2已经合成并且通过LC-UV-MS确定，以高拷贝数与泛素偶联。

  DOI：

  10.1039/c3ob42194e