6-Methyl-2-(trifluoromethyl)phenanthrene | 1417999-82-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 6-Methyl-2-(trifluoromethyl)phenanthrene
• 英文别名: 6-methyl-2-(trifluoromethyl)phenanthrene
• CAS: 1417999-82-6
• 化学式: C₁₆H₁₁F₃
• 分子量: 260.259
• InChiKey: VWNJXHPILMTNJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  在 碘 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 24.0h， 以98%的产率得到6-Methyl-2-(trifluoromethyl)phenanthrene
  参考文献：
  名称：

  Expeditious synthesis of fluorinated styrylbenzenes and polyaromatic hydrocarbons

  摘要：

  A series of fluorinated styrylbenzene derivatives were synthesized by the Mizoroki-Heck reaction using phosphine-free catalytic conditions or by adopting the one-pot Wittig-Heck reaction sequence. The fluorinated styrylbenzenes were converted into polyaromatic hydrocarbons such as phenanthrenes, [4]helicenes, and benzo[ghi]perylene by a modified photocyclization procedure involving I-2-THF condition. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.11.022

文献信息

• Expeditious synthesis of fluorinated styrylbenzenes and polyaromatic hydrocarbons
  作者：Ashutosh V. Bedekar、Anju R. Chaudhary、M. Shyam Sundar、Murali Rajappa

  DOI：10.1016/j.tetlet.2012.11.022

  日期：2013.1

  A series of fluorinated styrylbenzene derivatives were synthesized by the Mizoroki-Heck reaction using phosphine-free catalytic conditions or by adopting the one-pot Wittig-Heck reaction sequence. The fluorinated styrylbenzenes were converted into polyaromatic hydrocarbons such as phenanthrenes, [4]helicenes, and benzo[ghi]perylene by a modified photocyclization procedure involving I-2-THF condition. (C) 2012 Elsevier Ltd. All rights reserved.