9-hydroxyl[7]helicene | 1444418-31-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 9-hydroxyl[7]helicene
• 英文别名: Heptacyclo[16.12.0.02,15.03,12.04,9.021,30.024,29]triaconta-1,3(12),4,6,8,10,13,15,17,19,21(30),22,24,26,28-pentadecaen-16-ol；heptacyclo[16.12.0.02,15.03,12.04,9.021,30.024,29]triaconta-1,3(12),4,6,8,10,13,15,17,19,21(30),22,24,26,28-pentadecaen-16-ol
• CAS: 1444418-31-8
• 化学式: C₃₀H₁₈O
• 分子量: 394.472
• InChiKey: NLEPTMZNOCMNIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  31
• 可旋转键数：
  0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  9-Bromo<7>helicene 在 trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II) 、 potassium carbonate 、 2-二环己基磷-2,4,6-三异丙基联苯 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 以20%的产率得到9-hydroxyl[7]helicene
  参考文献：
  名称：

  Exploration of 9-bromo[7]helicene reactivity

  摘要：

  Exploration of 9-bromo[7]helicene reactivity mainly in Pd-catalyzed reactions is reported. Palladium catalyzed carbon-carbon and carbon-heteroatom coupling reactions provide a large portfolio of racemic helicenes bearing different functional groups in good to excellent yields. Many of the reactions were performed in the microwave reactor keeping reaction time to a minimum compared with conventional synthetic methods. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.05.039

文献信息

• Exploration of 9-bromo[7]helicene reactivity
  作者：Jaroslav Žádný、Petr Velíšek、Martin Jakubec、Jan Sýkora、Vladimír Církva、Jan Storch

  DOI：10.1016/j.tet.2013.05.039

  日期：2013.7

  Exploration of 9-bromo[7]helicene reactivity mainly in Pd-catalyzed reactions is reported. Palladium catalyzed carbon-carbon and carbon-heteroatom coupling reactions provide a large portfolio of racemic helicenes bearing different functional groups in good to excellent yields. Many of the reactions were performed in the microwave reactor keeping reaction time to a minimum compared with conventional synthetic methods. (C) 2013 Elsevier Ltd. All rights reserved.