2-hydroxy-O,N-dimethylnorbelladine | 1135087-59-0

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 石蒜科生物碱
• 英文名称: 2-hydroxy-O,N-dimethylnorbelladine
• 英文别名: 2R-hydroxy-O,N-dimethylnorbelladine；(I+/-R)-4-Hydroxy-I+/--[[[(3-hydroxy-4-methoxyphenyl)methyl]methylamino]methyl]benzenemethanol；5-[[[(2R)-2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylamino]methyl]-2-methoxyphenol
• CAS: 1135087-59-0
• 化学式: C₁₇H₂₁NO₄
• 分子量: 303.358
• InChiKey: XZFHDRJBRRZRFZ-INIZCTEOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  73.2
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 2-hydroxy-O,N-dimethylnorbelladine 以 甲醇 、 乙醚 为溶剂， 反应 72.0h， 以50%的产率得到
  参考文献：
  名称：

  Two New Alkaloids from Bulbs of Lycoris squamigera

  摘要：

  A new crinine-type alkaloid, squarnigine, and a norbelladine-type alkaloid were isolated from the bulbs of Lycoris squamigera (Amaryllidaceae), together with sixteen known alkaloids. Their structures were determined by spectroscopic analyses.

  DOI：

  10.3987/com-08-s(f)92

文献信息

• Two New Alkaloids from Bulbs of Lycoris squamigera
  作者：Hiromitsu Takayama、Eri Kinoshita、Mariko Kitajima、Noriyuki Kogure

  DOI：10.3987/com-08-s(f)92

  日期：——

  A new crinine-type alkaloid, squarnigine, and a norbelladine-type alkaloid were isolated from the bulbs of Lycoris squamigera (Amaryllidaceae), together with sixteen known alkaloids. Their structures were determined by spectroscopic analyses.