1-propyl-4-methylimidazole | 144748-25-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-propyl-4-methylimidazole
• 英文别名: 1H-Imidazole, 4-methyl-1-propyl；4-methyl-1-propylimidazole
• CAS: 144748-25-4
• 化学式: C₇H₁₂N₂
• mdl: MFCD18808447
• 分子量: 124.186
• InChiKey: SCHMIVXQOZZUFW-UHFFFAOYSA-N

物化性质

• 保留指数：
  1120

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.571
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-甲基咪唑 、 溴丙烷 在 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 反应 40.0h， 生成 1-propyl-4-methylimidazole 、 1-propyl-5-methylimidazole
  参考文献：
  名称：

  用于变温溶剂萃取的 1-Propyl-4(5)-Methylimidazole 异构体

  摘要：

  变温溶剂萃取 (TSSE) 利用具有温度依赖性水溶性的胺溶剂在较低温度下溶解水以浓缩或结晶盐水并分离各相。然后，加热溶剂混合物中的水以降低水溶性并引起溶剂和水之间的相分离。溶剂相和脱盐水相分离，再生的溶剂可以循环使用。当前 TSSE 溶剂的问题包括高溶剂水溶性和高溶剂挥发性。该项目使用高度可调的平台分子咪唑来创建两种 1-丁基咪唑异构体，特别是 1-丙基-4(5)-甲基咪唑，以测试它们对 TSSE 的有效性。咪唑类比目前最先进的同类产品吸收更多的水，但不要将产品水脱盐，并以较高浓度溶于水中。因此，虽然咪唑成为 TSSE 的有趣候选者，但需要进一步的工作来了解如何设计对 TSSE 应用有用的咪唑。

  DOI：

  10.3390/molecules27175583

文献信息

• [EN] ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE<br/>[FR] ORGANOSILANE, ORGANOSILANE IONIQUE, COMPOSITION DE MEMBRANE ET MEMBRANE
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2020254930A1

  公开（公告）日：2020-12-24

  A dihaloorganosilane is represented by the formula (I): Each X independently represents C1, Br, or I. Each Ar1 independently represents a phenylene group optionally substituted by 1 to 4 alkyl groups selected from methyl or ethyl. Each R1 independently represents an alkylene group having from 2 to 18 carbon atoms. Each R2 independently represents methyl or ethyl. Each R3 independently represents an alkylene group having from 1 to 18 carbon atoms. Each R4 independently represents an alkylene group having from 2 to 18 carbon atoms, and n is an integer in a range of 0 to 5, inclusive. Ionic organosilanes preparable from the dihaloorganosilanes are represented by the formula (II): Membrane compositions and membranes containing the ionic organosilanes are also disclosed.

  一种二卤有机硅烷的化学式为（I）：每个X独立地代表C1、Br或I。每个Ar1独立地代表一个苯基团，可选择地被1至4个甲基或乙基烷基取代。每个R1独立地代表具有2至18个碳原子的烷基基团。每个R2独立地代表甲基或乙基。每个R3独立地代表具有1至18个碳原子的烷基基团。每个R4独立地代表具有2至18个碳原子的烷基基团，n是一个范围在0至5之间的整数。可由二卤有机硅烷制备的离子有机硅烷的化学式为（II）：还公开了含有离子有机硅烷的膜组合物和膜。
• Regioselective N-alkylation of imidazoles with alcohols over zeolites
  作者：Yoshio Ono、Yuriko Izawa、Zi-hua Fu

  DOI：10.1039/c39950000009

  日期：——

  Vapour-phase alkylation of 4(5)-methylimidazole with MeOH over Y-zeolites selectivity gave 1,5-dimethylimidazole in high yield, while the Alkylation over Beta-zeolite gave 1,4-dimethylimidazole predominatly

  在 Y 型沸石上用 MeOH 对 4(5)-甲基咪唑进行气相烷基化，可获得高产率的 1,5-二甲基咪唑，而在 Beta 型沸石上进行烷基化则主要获得 1,4-二甲基咪唑。
• SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES
  申请人：Bayer Aktiengesellschaft

  公开号：US20200390100A1

  公开（公告）日：2020-12-17

  The present invention relates to substituted N-heterocyclyl- and N-heteroaryltetrahydropyrimidinones of the general formula (I) or salts thereof, where the radicals in the general formula (I) correspond to the definitions given in the description, and to the use thereof as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants.

  本发明涉及通式（I）或其盐的取代N-杂环烷基和N-杂芳基四氢嘧啶酮，其中通式（I）中的基团对应于描述中给出的定义，并将其用作除草剂，特别是用于控制作物中的阔叶杂草和/或杂草草，并/或作为植物生长调节剂，以影响作物的生长。
• 5-Phenyl-4-Methyl-Thiazol-2-Yl-Amine Derivatives as Inhibitors of Phosphatidylin Ositol 3 Kinase Enzymes (PI13) For Treatment of Inflammatory Diseases
  申请人：Bloomfield Graham Charles

  公开号：US20080280871A1

  公开（公告）日：2008-11-13

  in free or salt form, wherein R a , R b , R 2 , R 3 , R 4 and R 5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

  在自由或盐形式中，其中Ra，Rb，R2，R3，R4和R5具有规范中指示的含义，对于治疗由磷脂酰肌醇3-激酶介导的疾病是有用的。还描述了含有该化合物的药物组合物以及制备该化合物的过程。
• 5-PHENYL-4-METHYL-THIAZOL-2-YL-AMINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3 KINASE ENZYMES (PI3) FOR THE TREATMENT OF INFLAMMATORY DISEASES
  申请人：Bloomfield Graham Charles

  公开号：US20110124624A1

  公开（公告）日：2011-05-26

  Compounds of Formula I: in free or salt form, wherein R a , R b , R 2 , R 3 , R 4 and R 5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

  公式I的化合物：以自由或盐形式存在，其中Ra、Rb、R2、R3、R4和R5的含义如规范中所示，可用于治疗由磷脂酰肌醇3-激酶介导的疾病。还描述了含有这些化合物的制药组合物和制备这些化合物的过程。