| 139293-32-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 139293-32-6；139293-34-8；139293-36-0；139325-44-3
• 化学式: C₄₅H₄₆O₈
• 分子量: 714.855
• InChiKey: NXIJQAUIZWFSHW-LRSDVKCXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.31
• 重原子数：
  53.0
• 可旋转键数：
  18.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  81.68
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  、 异丙醇 在 trifluoromethanesulfonate 作用下， 以 乙腈 为溶剂， 反应 3.0h， 以90%的产率得到isopropyl 2,3,4,6-tetra-O-benzyl-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of β-O-glycosides using enol ether and imidate derived leaving groups. Emphasis on the use of nitriles as a solvent

  摘要：

  Two new methods of beta-glycoside synthesis using donors 2 and 3 that contain leaving groups derived from enol ether and imidates have been developed. Effect of nitriles as a solvent in directing mainly beta-glycosidations has been compared with various methods reported in the literature. Effectiveness of leaving group at low temperatures and participation of nitriles in the formation of nitrilium-nitrile conjugate has been emphasized.

  DOI：

  10.1016/s0040-4020(01)96047-8
• 作为产物：
  描述：

  2,3,4,6-四苄基-D-吡喃葡萄糖 、 苯丙炔酸乙酯 在 sodium hydride 作用下， 生成
  参考文献：
  名称：

  Synthesis of β-O-glycosides using enol ether and imidate derived leaving groups. Emphasis on the use of nitriles as a solvent

  摘要：

  Two new methods of beta-glycoside synthesis using donors 2 and 3 that contain leaving groups derived from enol ether and imidates have been developed. Effect of nitriles as a solvent in directing mainly beta-glycosidations has been compared with various methods reported in the literature. Effectiveness of leaving group at low temperatures and participation of nitriles in the formation of nitrilium-nitrile conjugate has been emphasized.

  DOI：

  10.1016/s0040-4020(01)96047-8