10,11-Dimethoxytriphenylene-2,3,6,7-tetrol | 1206881-90-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 10,11-Dimethoxytriphenylene-2,3,6,7-tetrol
• 英文别名: 10,11-dimethoxytriphenylene-2,3,6,7-tetrol
• CAS: 1206881-90-4
• 化学式: C₂₀H₁₆O₆
• 分子量: 352.343
• InChiKey: RSUAGXNHVUQESD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  三氟甲磺酸酐 、 10,11-Dimethoxytriphenylene-2,3,6,7-tetrol 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 以68%的产率得到
  参考文献：
  名称：

  Facile Cyclization of Terphenyl to Triphenylene: A New Chemodosimeter for Fluoride Ions

  摘要：

  Terphenyl derivatives 3 and 4 having OTBS groups have been synthesized via a Suzuki-Miyura coupling reaction, These compounds undergo unprecedented irreversible cyclization to symmetrically/unsymmetrically substituted triphenylenes while carrying out the deprotection of OTBS groups using tetrabutylammonium fluoride. Terphenyl 3 also serves as a new chemodosimeter for fluoride ions.

  DOI：

  10.1021/ol902861b
• 作为产物：
  描述：

  [4-[2-[3,4-Bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]-4,5-dimethoxyphenyl]-2-[tert-butyl(dimethyl)silyl]oxyphenoxy]-tert-butyl-dimethylsilane 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以91%的产率得到10,11-Dimethoxytriphenylene-2,3,6,7-tetrol
  参考文献：
  名称：

  Facile Cyclization of Terphenyl to Triphenylene: A New Chemodosimeter for Fluoride Ions

  摘要：

  Terphenyl derivatives 3 and 4 having OTBS groups have been synthesized via a Suzuki-Miyura coupling reaction, These compounds undergo unprecedented irreversible cyclization to symmetrically/unsymmetrically substituted triphenylenes while carrying out the deprotection of OTBS groups using tetrabutylammonium fluoride. Terphenyl 3 also serves as a new chemodosimeter for fluoride ions.

  DOI：

  10.1021/ol902861b

文献信息

• Facile Cyclization of Terphenyl to Triphenylene: A New Chemodosimeter for Fluoride Ions
  作者：Vandana Bhalla、Hardev Singh、Manoj Kumar

  DOI：10.1021/ol902861b

  日期：2010.2.5

  Terphenyl derivatives 3 and 4 having OTBS groups have been synthesized via a Suzuki-Miyura coupling reaction, These compounds undergo unprecedented irreversible cyclization to symmetrically/unsymmetrically substituted triphenylenes while carrying out the deprotection of OTBS groups using tetrabutylammonium fluoride. Terphenyl 3 also serves as a new chemodosimeter for fluoride ions.