6-Deoxy-D-altro-heptose | 59401-37-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-Deoxy-D-altro-heptose
• 英文别名: (2S,3R,4R,5R)-2,3,4,5,7-pentahydroxyheptanal
• CAS: 59401-37-5
• 化学式: C₇H₁₄O₆
• 分子量: 194.18
• InChiKey: YTDXCLRWYXTNRN-GBNDHIKLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  118
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• Capsule composition for use as immunogen against Campylobacter jejuni
  申请人：The United States of America as Represented by The Secretary of the Navy

  公开号：EP2786763A1

  公开（公告）日：2014-10-08

  1. The invention relates to an immunogenic composition, composed of an isolated polymer, wherein said polymer is a repeating disaccharide having the formula →4)P→3-alpha-D-Gal-1→3-P→2/7-6⁢d-alpha-D-ido-Hep-(1→, or →4)P→3-alpha-D-Gal-1→3-P→2-L-glycero-alpha-D-ido-Hep-(1→, wherein P is O-methyl phosphoramidate present in non-stoichiometric amounts.

  本发明涉及一种由分离聚合物组成的免疫原组合物，其中所述聚合物是一种重复二糖，其式为：→4)P→3-α-D-Gal-1→3-P→2/7-6d-α-D-ido-Hep-(1→、 or →4)P→3-alpha-D-Gal-1→3-P→2-L-glycero-alpha-D-ido-Hep-(1→, 其中 P 为 O-甲基磷酰胺，以非几何量存在。
• Immunogenic composition against Campylobacter jejuni
  申请人：The United States of America as Represented by the Secretary of the Navy

  公开号：US10363213B2

  公开（公告）日：2019-07-30

  The inventive subject matter relates to an immunogenic composition against Campylobacter jejuni comprising isolated capsule polysaccharide from selected pathogenic Campylobacter jejuni strains. The inventive subject matter also relates to methods of using the polysaccharide compositions in inducing an anti-C. jejuni immune response.

  本发明的主题涉及一种抗空肠弯曲菌的免疫原组合物，该组合物包含从选定的致病性空肠弯曲菌菌株中分离出的胶囊多糖。本发明主题还涉及使用多糖组合物诱导抗空肠弯曲菌免疫反应的方法。
• Processes and host cells for genome, pathway, and biomolecular engineering
  申请人：enEvolv, Inc.

  公开号：US10370654B2

  公开（公告）日：2019-08-06

  The present disclosure provides compositions and methods for genomic engineering.

  本公开提供了基因组工程的组合物和方法。
• IMMUNOGENIC CAPSULE COMPOSITION FOR USE AS A VACCINE COMPONENT AGAINST CAMPYLOBACTER JEJUNI
  申请人：The United States of America as represented by the Secretary of the Navy

  公开号：EP1933865B1

  公开（公告）日：2016-03-09
• CAPSULE COMPOSITION FOR USE AS IMMUNOGEN AGAINST CAMPYLOBACTER JEJUNI
  申请人：The United States Of America As Represented By The Secretary Of The Navy

  公开号：EP2185189B1

  公开（公告）日：2017-09-27