| 1268520-49-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• CAS: 1268520-49-5
• 化学式: C₂₃H₁₆Cl₂O₄
• 分子量: 427.284
• InChiKey: BREWJLKBUBLSRV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.28
• 重原子数：
  29.0
• 可旋转键数：
  4.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  59.67
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  在 水 、 mercury dichloride 作用下， 以 二甲基亚砜 为溶剂， 反应 1.0h， 以82%的产率得到2,7-dichloro-6-hydroxy-9-[2-(hydroxymethyl)phenyl]xanthen-3-one
  参考文献：
  名称：

  Development and Applications of Fluorogenic Probes for Mercury(II) Based on Vinyl Ether Oxymercuration

  摘要：

  Mercury is a major threat to the environment and to human health. It is highly desirable to develop a user-friendly kit for on-site mercury detection. Such a method must be able to detect mercury below the threshold levels for drinking water, 1-2 ppb. We developed a fluorescence method based on the oxymercuration of vinyl ethers to detect mercury in dental and environmental samples. Chloride ions interfered with the oxymercuration reaction, but the addition of AgNO3 solved this problem. Fine electronic and structural tuning led to the development of a more responsive probe that was less sensitive to chloride ion interference. This second-generation probe could detect 1 ppb mercury ions in water.

  DOI：

  10.1021/ja108028m