3-iodo-N-(1-methyl-2-methylthioethyl)phthalamidic acid | 317813-26-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-iodo-N-(1-methyl-2-methylthioethyl)phthalamidic acid
• 英文别名: 3-iodo-N-(1-methyl-2-methylsulfanyl-ethyl)-phthalamic acid；3-iodo-2-(1-methylsulfanylpropan-2-ylcarbamoyl)benzoic acid
• CAS: 317813-26-6
• 化学式: C₁₂H₁₄INO₃S
• 分子量: 379.219
• InChiKey: RVAPKCGXUABJEL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  91.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-[3-(4-chlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-5-yl]-2-methylaniline 、 3-iodo-N-(1-methyl-2-methylthioethyl)phthalamidic acid 在 三氟乙酸酐 作用下， 以 二氯甲烷 为溶剂， 反应 14.0h， 生成 N1-[4-[3-(4-chlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-5-yl]-2-methylphenyl]-3-iodo-N2-(1-methyl-2-methylthioethyl)phthalic diamide
  参考文献：
  名称：

  EP1538138

  摘要：

  公开号：
• 作为产物：
  描述：

  4-碘异苯并呋喃-1,3-二酮 、 (S)-1-(methylthio)propan-2-amine 、 sodium hydroxide 在 水 、 甲基叔丁基醚 、 氯化钠 、 Sodium sulfate-III 作用下， 以 N,N-二甲基乙酰胺 、 水 为溶剂， 反应 15.17h， 生成 3-iodo-N-(1-methyl-2-methylthioethyl)phthalamidic acid
  参考文献：
  名称：

  Optically active phthalamides

  摘要：

  化学式为(I)的新型光学活性邻苯二酰胺化合物，其中A、q、R1、R2、E1、E2、X、m、Y、n和Z如描述中所定义，制备这些化合物的方法以及它们用于控制害虫的用途。

  公开号：

  US20090118375A1

文献信息

• [EN] N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES<br/>[FR] DERIVES DE N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE ET COMPOSES INSECTICIDES ASSOCIES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2005095351A1

  公开（公告）日：2005-10-13

  Novel benzenedicarboxamides of the formula (I) wherein X represents hydrogen, halogen atom, nitro, C1-6alkylsulfonyloxy, C1-6alkylsulfinyl, C1-6alkylsulfenyl or C1-6alkylsulfonyl, R1 represents C1-6alkyl, C1-6alkylthio-C1-6alkyl, C1-6alkylsulfinyl- C1-6alkyl or C1-6 alkylsulfonyl- C1-6alkyl, Y represents halogen or C1-6alkyl, m represents 0 or 1, A represents O, S, SO, SO2, CH2 or CH(CH3), and Q represents a 5- or 6-membered heterocyclic group that contains at least one hetero atom selected from the group consisting of N, O and S and can be optionally substituted; processes for their preparation, their intermediates and their use as insecticides.

  式（I）中的新型苯二甲酰胺，其中X代表氢、卤素原子、硝基、C1-6烷基磺酰氧基、C1-6烷基亚砜基、C1-6烷基硫基或C1-6烷基磺基，R1代表C1-6烷基、C1-6烷基硫基-C1-6烷基、C1-6烷基亚砜基-C1-6烷基或C1-6烷基磺酰基-C1-6烷基，Y代表卤素或C1-6烷基，m代表0或1，A代表O、S、SO、SO2、CH2或CH(CH3)，Q代表含有至少一种异原子（N、O和S）的5-或6元杂环基，并可选择性地取代；它们的制备方法、它们的中间体以及它们作为杀虫剂的用途。
• OPTICALLY ACTIVE PHTHALAMIDE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL INSECTICIDE, AND METHOD OF USING THE SAME
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP1782689A1

  公开（公告）日：2007-05-09

  The present invention relates to an optically active phthalamide derivative represented by the following formula (I): (wherein each of R1 and R2 represents H, optionally substituted C1-C6 alkyl, or C1-C6 alkoxycarbonyl; R3 represents C1-C6 alkyl; A represents H, C1-C6 alkyl, C3-C6 alkenyl, C3-C6 alkynyl, optionally substituted phenoxy C1-C6 alkyl, or the like; p represents 0, 1, 2, 3, or 4; q represents 0, 1, or 2; X represents halogen, CN, NH2, C1-C6 alkyl, C2-C6 alkenyl, C1-C6 alkylthio, or the like; m represents 0, 1, 2, 3, or 4; Y represents halogen, CN, NH2, C1-C6 alkyl, optionally substituted phenyl, or the like; n represents 1, 2, 3, 4, or 5; and each of Z1 and Z2 represents C-Y or N; and further X and Y may form a condensed ring together with carbon atoms adjacent thereto on a phenyl ring), a salt thereof, an agrohorticultural insecticide comprising the above derivative as an active ingredient, and a method of use thereof. The optically active phthalamide derivative of the present invention has superior control activity as an agrohorticultural insecticide, and has excellent effects even when the insectide is used in admixture with other insecticides.

  本发明涉及一种光学活性的邻苯二甲酰胺衍生物，其表示为以下公式（I）： 其中，R1和R2中的每一个代表H，可选取代的C1-C6烷基，或C1-C6烷氧羰基；R3代表C1-C6烷基；A代表H，C1-C6烷基，C3-C6烯基，C3-C6炔基，可选取代的苯氧基C1-C6烷基等；p代表0、1、2、3或4；q代表0、1或2；X代表卤素，CN，NH2，C1-C6烷基，C2-C6烯基，C1-C6烷硫基等；m代表0、1、2、3或4；Y代表卤素，CN，NH2，C1-C6烷基，可选取代的苯基等；n代表1、2、3、4或5；Z1和Z2中的每一个代表C-Y或N；并且X和Y可以与相邻苯环上的碳原子一起形成紧缩环。本发明的光学活性邻苯二甲酰胺衍生物作为农业园艺杀虫剂具有优异的控制活性，即使与其他杀虫剂混合使用也具有良好的效果。本发明还涉及一种以上述衍生物为活性成分的农业园艺杀虫剂，以及其使用方法。
• Substituted benzanilide compound and noxious organism controlling agent
  申请人：Mita Takeshi

  公开号：US20050250822A1

  公开（公告）日：2005-11-10

  The present invention is to provide a novel agricultural chemical, in particular an insecticide or an acaricide, and relates to a substituted benzanilide compound represented by the formula (1): wherein G represents a ring such as G-7, G-13 and G-71, etc., W 1 and W 2 each independently represent oxygen atom or sulfur atom, X represents halogen atom, etc., Y represents C 1 to C 6 alkyl, etc., R 1 , R 2 and R 3 each independently represent hydrogen atom, a C 1 to C 12 alkyl or a C 1 to C 6 alkylthio(C 1 to C 6 ) alkyl, etc., R 4 , R 5 , R 6a and R 6b each independently represent hydrogen atom, a C 1 to C 6 alkyl, a C 1 to C 6 haloalkyl or phenyl which may be substituted by (Z 2 ) p1 , etc., R 6i , R 6j and R 6k each independently represent hydrogen atom or halogen atom, etc., Z 2 represents halogen atom, a C 1 to C 6 haloalkoxy or a C 1 to C 6 alkylsulfonyl, etc., m and n each independently represent integer of 0 to 4, and p1 represents integer of 1 to 5, or a salt thereof, and a noxious organism controlling agent containing these.

  本发明提供了一种新型农药化学品，特别是一种杀虫剂或螨虫剂，涉及一种由式(1)表示的取代苯甲酰胺化合物：其中G代表环，例如G-7、G-13和G-71等，W1和W2分别独立地表示氧原子或硫原子，X表示卤素原子等，Y表示C1到C6烷基等，R1、R2和R3分别独立地表示氢原子、C1到C12烷基或C1到C6烷基硫（C1到C6）烷基等，R4、R5、R6a和R6b分别独立地表示氢原子、C1到C6烷基、C1到C6卤代烷基或苯基，该苯基可以被（Z2）p1等取代，R6i、R6j和R6k分别独立地表示氢原子或卤素原子等，Z2表示卤素原子、C1到C6卤代氧基或C1到C6烷基磺酰基等，m和n分别独立地表示0到4的整数，p1表示1到5的整数，或其盐，以及含有这些的有害生物控制剂。
• Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same
  申请人：Nakao Hayami

  公开号：US20080051457A1

  公开（公告）日：2008-02-28

  The present invention relates to an optically active phthalamide derivative represented by the following formula (I): (wherein each of R 1 and R 2 represents H, optionally substituted C1-C6 alkyl, or C1-C6 alkoxycarbonyl; R 3 represents C1-C6 alkyl; A represents H, C1-C6 alkyl, C3-C6 alkenyl, C3-C6 alkynyl, optionally substituted phenoxy C1-C6 alkyl, or the like; p represents 0, 1, 2, 3, or 4; q represents 0, 1, or 2; X represents halogen, CN, NH 2 , C1-C6 alkyl, C2-C6 alkenyl, C1-C6 alkylthio, or the like; m represents 0, 1, 2, 3, or 4; Y represents halogen, CN, NH 2 , C1-C6 alkyl, optionally substituted phenyl, or the like; n represents 1, 2, 3, 4, or 5; and each of Z 1 and Z 2 represents C—Y or N; and further X and Y may form a condensed ring together with carbon atoms adjacent thereto on a phenyl ring), a salt thereof, an agrohorticultural insecticide comprising the above derivative as an active ingredient, and a method of use thereof. The optically active phthalamide derivative of the present invention has superior control activity as an agrohorticultural insecticide, and has excellent effects even when the insecticide is used in admixture with other insecticides.

  本发明涉及一种光学活性的邻苯二甲酰胺衍生物，其表示为以下式子（I）： 其中，R1和R2分别表示氢、可选取代的C1-C6烷基或C1-C6烷氧羰基；R3表示C1-C6烷基；A表示氢、C1-C6烷基、C3-C6烯基、C3-C6炔基、可选取代的苯氧基C1-C6烷基或类似物；p表示0、1、2、3或4；q表示0、1或2；X表示卤素、CN、NH2、C1-C6烷基、C2-C6烯基、C1-C6烷硫基或类似物；m表示0、1、2、3或4；Y表示卤素、CN、NH2、C1-C6烷基、可选取代的苯基或类似物；n表示1、2、3、4或5；Z1和Z2分别表示C-Y或N；并且X和Y可以与相邻的苯环上的碳原子一起形成一个紧缩环。 本发明的光学活性邻苯二甲酰胺衍生物作为农业园艺杀虫剂具有优异的控制活性，即使与其他杀虫剂混合使用，也有出色的效果。本发明还涉及一种包含上述衍生物作为活性成分的农业园艺杀虫剂和其使用方法。
• BENZANILIDES WITH INSECTICIDAL ACTIVITY
  申请人：Wada Katsuaki

  公开号：US20100062937A1

  公开（公告）日：2010-03-11

  Benzanilides of the formula: in which X represents hydrogen, halogen, nitro, C 1-6 alkylthio, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyl or C 1-6 alkylsulfonyloxy; Y represents halogen or C 1-6 alkyl; R 1 represents C 1-6 alkyl, C 1-6 alkylthio C 1-6 alkyl, C 1-6 alkylsulfinyl-C 1-6 alkyl or C 1-6 alkylsulfonyl-C 1-6 alkyl; R 2 represents hydrogen, C 1-6 alkyl or C 1-6 haloalkyl; R 3 represents hydrogen or hydroxy; W represents CH or N; and Q represents optionally substituted phenyl or optionally substituted pyridyl wherein the substituent is at least one group selected from the group consisting of halogen, C 1-6 haloalkyl, C 1-6 haloalkoxy, C 1-6 haloalkylthio, C 1-6 haloalkylsulfinyl and C 1-6 haloalkylsulfoxy; provided that when R 3 is hydroxy, R 2 is not C 1-6 alkyl, or when R 2 is C 1-6 haloalkyl, R 3 is hydroxy, W is CH, and the substituents of Q are two or more C 1-6 haloalkyl. Insecticides comprising the benzanilides are herein provided.

  公式为Benzanilides:其中X代表氢、卤素、硝基、C1-6烷基硫、C1-6烷基亚磺酰、C1-6烷基磺酰或C1-6烷基磺酰氧；Y代表卤素或C1-6烷基；R1代表C1-6烷基、C1-6烷基硫、C1-6烷基亚磺酰-C1-6烷基或C1-6烷基磺酰-C1-6烷基；R2代表氢、C1-6烷基或C1-6卤代烷基；R3代表氢或羟基；W代表CH或N；Q代表可选取代的苯基或可选取代的吡啶基，其中取代基至少为以下群中的一种：卤素、C1-6卤代烷基、C1-6卤代烷氧基、C1-6卤代烷基硫、C1-6卤代烷基亚磺酰和C1-6卤代烷基磺酰氧；但当R3为羟基时，R2不是C1-6烷基，或当R2为C1-6卤代烷基，R3为羟基，W为CH，且Q的取代基为两个或以上的C1-6卤代烷基时，不适用。本文提供了含有Benzanilides的杀虫剂。