N-(4-Methoxy-pyridin-2-yl)-N'-phenyl-hydrazine | 533935-52-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-Methoxy-pyridin-2-yl)-N'-phenyl-hydrazine
• 英文别名: 1-(4-Methoxypyridin-2-yl)-2-phenylhydrazine；1-(4-methoxypyridin-2-yl)-2-phenylhydrazine
• CAS: 533935-52-3
• 化学式: C₁₂H₁₃N₃O
• 分子量: 215.255
• InChiKey: SWNWVJBAHFMVIK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  46.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  四氢呋喃 、 二氯甲烷 、 molybdenum hexacarbonyl 、 N-(4-Methoxy-pyridin-2-yl)-N'-phenyl-hydrazine 以 四氢呋喃 为溶剂， 以31%的产率得到cis-Mo(CO)4(4-methoxy-2(phenylhydrazino)pyridine)
  参考文献：
  名称：

  Tetracarbonylmolybdenum complexes of 2-(phenylhydrazino)pyridine ligands.

  摘要：

  The 2-(phenythydrazino)pyridine (2-PHP) complexes cis-Mo(CO)(4)(X-2-(phenylhydrazino)pyridine) (X = 4-CH3O, 4-CH3, H, 4-Cl, 5-Br, 6-CH3, 4,6-(CH3)(2)) and CiS-MO(CO)(4)(2-(2-CH3-phenylhydrazino)pyridine) have been synthesized and characterized. The properties of these complexes are compared with those of the analogous 2-(phenylazo)pyridine (2-PAP) complexes. The lack of the pi-accepting azo group in the 2-PHP ligands leads to less stable complexes, including the inability even to isolate the complex with X = CF3. The 2-PHP complexes show very good correlations among the Mo-95-NMR chemical shift, the sum of the carbonyl stretching frequencies, and the Hammett sigma parameter for the pyridyl substituents. There is also an excellent correlation (r = 0.978, n = 7) of the Mo-95 chemical shift of the 2-PHP complexes with the shift for the 2-PAP complexes. The failure of the complexes with X 6-CH3 or 4,6-(CH3)(2) or the complexcis-Mo(CO)(4)(2-(2-CH3-phenylhydrazino)pyridine) to fit some of the correlations is attributed to steric or electronic effects. The 2-hydrazinopyridine complex cis-Mo(CO)(4)(H2NHNC5H4N) also was characterized. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(02)02140-x
• 作为产物：
  描述：

  (4-Methoxy-pyridin-2-yl)-phenyl-diazene 在 ammonium hydroxide 、 甲脒 作用下， 以 甲醇 为溶剂， 以55%的产率得到N-(4-Methoxy-pyridin-2-yl)-N'-phenyl-hydrazine
  参考文献：
  名称：

  Tetracarbonylmolybdenum complexes of 2-(phenylhydrazino)pyridine ligands.

  摘要：

  The 2-(phenythydrazino)pyridine (2-PHP) complexes cis-Mo(CO)(4)(X-2-(phenylhydrazino)pyridine) (X = 4-CH3O, 4-CH3, H, 4-Cl, 5-Br, 6-CH3, 4,6-(CH3)(2)) and CiS-MO(CO)(4)(2-(2-CH3-phenylhydrazino)pyridine) have been synthesized and characterized. The properties of these complexes are compared with those of the analogous 2-(phenylazo)pyridine (2-PAP) complexes. The lack of the pi-accepting azo group in the 2-PHP ligands leads to less stable complexes, including the inability even to isolate the complex with X = CF3. The 2-PHP complexes show very good correlations among the Mo-95-NMR chemical shift, the sum of the carbonyl stretching frequencies, and the Hammett sigma parameter for the pyridyl substituents. There is also an excellent correlation (r = 0.978, n = 7) of the Mo-95 chemical shift of the 2-PHP complexes with the shift for the 2-PAP complexes. The failure of the complexes with X 6-CH3 or 4,6-(CH3)(2) or the complexcis-Mo(CO)(4)(2-(2-CH3-phenylhydrazino)pyridine) to fit some of the correlations is attributed to steric or electronic effects. The 2-hydrazinopyridine complex cis-Mo(CO)(4)(H2NHNC5H4N) also was characterized. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(02)02140-x

文献信息

• Tetracarbonylmolybdenum complexes of 2-(phenylhydrazino)pyridine ligands.
  作者：Martin N Ackermann、Keara B Moore、Amanda S Colligan、Jennifer A Thomas-Wohlever、Kirk J Warren

  DOI：10.1016/s0022-328x(02)02140-x

  日期：2003.2

  The 2-(phenythydrazino)pyridine (2-PHP) complexes cis-Mo(CO)(4)(X-2-(phenylhydrazino)pyridine) (X = 4-CH3O, 4-CH3, H, 4-Cl, 5-Br, 6-CH3, 4,6-(CH3)(2)) and CiS-MO(CO)(4)(2-(2-CH3-phenylhydrazino)pyridine) have been synthesized and characterized. The properties of these complexes are compared with those of the analogous 2-(phenylazo)pyridine (2-PAP) complexes. The lack of the pi-accepting azo group in the 2-PHP ligands leads to less stable complexes, including the inability even to isolate the complex with X = CF3. The 2-PHP complexes show very good correlations among the Mo-95-NMR chemical shift, the sum of the carbonyl stretching frequencies, and the Hammett sigma parameter for the pyridyl substituents. There is also an excellent correlation (r = 0.978, n = 7) of the Mo-95 chemical shift of the 2-PHP complexes with the shift for the 2-PAP complexes. The failure of the complexes with X 6-CH3 or 4,6-(CH3)(2) or the complexcis-Mo(CO)(4)(2-(2-CH3-phenylhydrazino)pyridine) to fit some of the correlations is attributed to steric or electronic effects. The 2-hydrazinopyridine complex cis-Mo(CO)(4)(H2NHNC5H4N) also was characterized. (C) 2002 Elsevier Science B.V. All rights reserved.