2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl hydroxyacetate | 475993-56-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl hydroxyacetate
• 英文别名: 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethyl 2-hydroxyacetate
• CAS: 475993-56-7
• 化学式: C₁₀H₂₀O₇
• 分子量: 252.265
• InChiKey: MPTALSHDOHEHED-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  17
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  94.4
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
  申请人：——

  公开号：US20030152630A1

  公开（公告）日：2003-08-14

  PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insoluble materials; and they also form bioerodible matrices for the sustained release of active agents, especially when the POE block(s) contain at least one unit containing an &agr;-hydroxy acid.

  PEG-POE，PEG-POE-PEG和POE-PEG-POE嵌段共聚物具有亲水和疏水区块。它们在水溶液中形成胶束，适用于包封或溶解疏水或不溶于水的材料；它们还形成可生物降解的基质，用于持续释放活性剂，特别是当POE区块中至少含有一个含有α-羟基酸的单元时。
• PEG-POE, PEG-POE-PEG, AND POE-PEG-POE BLOCK COPOLYMERS
  申请人：AP Pharma, Inc.

  公开号：EP1395626A1

  公开（公告）日：2004-03-10
• [EN] PEG-POE, PEG-POE-PEG, AND POE-PEG-POE BLOCK COPOLYMERS<br/>[FR] COPOLYMERES SEQUENCES PEG-POE, PEG-POE-PEG ET POE-PEG-POE
  申请人：AP PHARMA INC

  公开号：WO2002092661A1

  公开（公告）日：2002-11-21

  PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insoluble materials; and they also form bioerodible matrices for the sustained release of active agents, especially when the POE block(s) contain at least one unit containing an α-hydroxy acid.