4-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonamide | 874839-04-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonamide
• 英文别名: 4-[5-(trifluoromethyl)pyridin-2-yl]oxybenzenesulfonamide
• CAS: 874839-04-0
• 化学式: C₁₂H₉F₃N₂O₃S
• 分子量: 318.27
• InChiKey: UWMKWABVZPQPLO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  90.7
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• Indoline derivatives and method for using and producing the same
  申请人：ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US10654802B2

  公开（公告）日：2020-05-19

  The present invention relates to a compound of the formula: where n, R1 and R2 are those defined herein. The present invention also relates to use of a compound of Formula 1 in treating a clinical condition associated with fibrotic disorder.

  本发明涉及式 1 的化合物，其中 n、R1 和 R2 为本文所定义者。本发明还涉及式 1 化合物在治疗与纤维化紊乱有关的临床病症中的用途。
• INDOLINE DERIVATIVES AND METHOD FOR USING AND PRODUCING THE SAME
  申请人：ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US20190135746A1

  公开（公告）日：2019-05-09

  The present invention relates to a compound of the formula: where n, R and R are those defined herein. The present invention also relates to use of a compound of Formula 1 in treating a clinical condition associated with fibrotic disorder.