3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine | 213550-82-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine
• 英文别名: 3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine
• CAS: 213550-82-4
• 化学式: C₉H₁₁IN₂O
• 分子量: 290.1
• InChiKey: RKVRGRXOYDTUEY-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  34.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Dry eye treatments
  申请人：Oyster Point Pharma, Inc.

  公开号：US10456396B2

  公开（公告）日：2019-10-29

  Described herein are methods and pharmaceutical formulations for treating dry eye disease.

  本文描述的是治疗干眼症的方法和药物制剂。
• Methods of increasing lacrimal proteins
  申请人：Oyster Point Pharma, Inc.

  公开号：US11224598B2

  公开（公告）日：2022-01-18

  Described herein are methods and pharmaceutical formulations for treating dry eye disease.

  本文描述的是治疗干眼症的方法和药物制剂。
• METHODS OF TREATING OCULAR CONDITIONS
  申请人：Oyster Point Pharma, Inc.

  公开号：EP3209295B1

  公开（公告）日：2020-12-09
• NEURONAL IMAGING AND TREATMENT
  申请人：BEN-HAIM Shlomo

  公开号：US20150366523A1

  公开（公告）日：2015-12-24

  A method is disclosed herein for imaging at least one autonomic nervous system synaptic center in a subject, as well as a method of diagnosing and/or monitoring a medical condition or disease associated with an autonomic nervous system, and a method of guiding a therapy of such a medical condition or disease. The methods comprise administering to the subject a radioactive tracer which selectively binds to autonomic nervous system synapses; measuring radioactive emission of the tracer to obtain data describing a distribution of the tracer in the body; and analyzing the data in order to identify at least one region exhibiting a high concentration of the tracer. Further disclosed herein are radioactive tracers, uses thereof, and an apparatus, for use in a method disclosed herein.
• OCULAR DISCOMFORT
  申请人：Oyster Point Pharma, Inc.

  公开号：US20160106665A1

  公开（公告）日：2016-04-21

  Described herein are methods and pharmaceutical formulations for improving ocular discomfort.