S-8-Azaadenosiyl-L-homocystein | 59987-42-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: S-8-Azaadenosiyl-L-homocystein
• 英文别名: S-[1-(7-amino-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-β-D-1-deoxy-ribofuranos-5-yl]-homocysteine；S-8-azaadenosyl-l-homocysteine；(2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(7-aminotriazolo[4,5-d]pyrimidin-3-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]butanoic acid
• CAS: 59987-42-7
• 化学式: C₁₃H₁₉N₇O₅S
• 分子量: 385.404
• InChiKey: ZTAQMRJGWYNIJC-MACXSXHHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  221
• 氢给体数：
  5
• 氢受体数：
  12

文献信息

• CHEMOENZYMATIC SYNTHESIS OF S-NUCLEOSYL AMINO ACIDS (SNA), ANALOGS OF S-ADENOSYL-L-METHIONINE AND S-ADENOSYL-L- HOMOCYSTEINE AND USES THEREOF
  申请人：ALBERT EINSTEIN COLLEGE OF MEDICINE

  公开号：US20200239921A1

  公开（公告）日：2020-07-30

  Disclosed are methods for chemoenzymatic synthesis of S-Nucleosyl Amino acid probes (SNA), analogs of S-adeno-syl-L-methionine and S-adenosyl-L-homo-cysteine, analogs synthesized by the methods, and uses thereof.
• [EN] CHEMOENZYMATIC SYNTHESIS OF S-NUCLEOSYL AMINO ACIDS (SNA), ANALOGS OF S-ADENOSYL-L-METHIONINE AND S-ADENOSYL-L-HOMOCYSTEINE AND USES THEREOF<br/>[FR] SYNTHÈSE CHIMIOENZYMATIQUE D'ACIDES AMINÉS S-NUCLÉOSYLE (SNA), D'ANALOGUES DE LA S-ADÉNOSYL-L-MÉTHIONINE ET DE LA S-ADÉNOSYL-L-HOMOCYSTÉINE ET LEURS UTILISATIONS
  申请人：ALBERT EINSTEIN COLLEGE MEDICINE INC

  公开号：WO2017136194A1

  公开（公告）日：2017-08-10

  Disclosed are methods for chemoenzymatic synthesis of S-Nucleosyl Amino acid probes (SNA), analogs of S-adenosyl-L-methionine and S-adenosyl-L -homocysteine, analogs synthesized by the methods, and uses thereof.