5-bromo-2-(3-methoxy-phenoxy)-thiazole | 1384191-70-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-bromo-2-(3-methoxy-phenoxy)-thiazole
• 英文别名: 5-Bromo-2-(3-methoxyphenoxy)-1,3-thiazole
• CAS: 1384191-70-1
• 化学式: C₁₀H₈BrNO₂S
• 分子量: 286.149
• InChiKey: DEDMUARICMOEQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  59.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS<br/>[FR] COMPOSÉS THIAZOLES UTILES COMME INHIBITEURS DE L'ACÉTYL-CoA CARBOXYLASE (ACC)
  申请人：JUBILANT BIOSYS LTD

  公开号：WO2012090219A2

  公开（公告）日：2012-07-05

  The present invention provides thiazole compounds of Formula I or its pharmaceutically acceptable salts, prodrugs, solvates, N-oxide thereof; solvates of pharmaceutically acceptable salts and N-oxides; pharmaceutically acceptable salts of N-oxides, or prodrugs; or combination or mixtures thereof; (I) The present invention further provides a method for preventing or treating a condition that responds to an Acetyl-CoA Carboxylase (ACC) inhibitor by using compounds of formula (I) or ), its pharmaceutically acceptable salts, prodrugs, solvates, N-oxide thereof; solvates of pharmaceutically acceptable salts and N-oxides; pharmaceutically acceptable salts of N-oxides, or prodrugs; or combination or mixtures thereof.