ethyl 3-[2-[(4-ethoxy-4-oxobutan-2-ylidene)amino]ethylimino]butanoate | 10054-25-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 3-[2-[(4-ethoxy-4-oxobutan-2-ylidene)amino]ethylimino]butanoate
• 英文别名: (3E,3'E)-diethyl 3,3'-(ethane-1,2-diylbis(azan-1-yl-1-ylidene))dibutanoate；3,3'-(ethane-1,2-diyldiimino)-dibutenoate
• CAS: 10054-25-8
• 化学式: C₁₄H₂₄N₂O₄
• 分子量: 284.356
• InChiKey: VLRJVPYRATZLPD-JOBJLJCHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.81
• 重原子数：
  20.0
• 可旋转键数：
  9.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  77.32
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  ethyl 3-[2-[(4-ethoxy-4-oxobutan-2-ylidene)amino]ethylimino]butanoate 在 potassium carbonate 、 potassium iodide 作用下， 以 丙酮 为溶剂， 反应 42.5h， 生成 diethyl 5,5'-bis(ethoxycarbonylmethoxy)-2,2'-dimethyl-1,1'-(ethane-1,2-diyl)di(1H-indole)-3,3'-dicarboxylate
  参考文献：
  名称：

  Gadaginamath; Shyadligeri, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000, vol. 39, # 1, p. 31 - 35

  摘要：

  DOI：
• 作为产物：
  描述：

  乙酰乙酸乙酯 、 乙二胺 以 乙醇 为溶剂， 反应 6.0h， 生成 ethyl 3-[2-[(4-ethoxy-4-oxobutan-2-ylidene)amino]ethylimino]butanoate
  参考文献：
  名称：

  Tetradentate Schiff-base ruthenium(III) complexes containing triphenylphosphine/arsine as coligands: study of physico-chemical, spectrometric, catalytic, and biocidal activities

  摘要：

  A series of air-stable, low-spin Ru(III) octahedral complexes [RuX(EPh3)L] (where X = Cl/Br; E = P/As; and L = dibasic tetradentate Schiff base derived by condensation of ethylenediamine with acetoacetanilide/acetoacetotoluidide/ethylacetoacetate in 1 : 2 molar ratio in ethanol) have been synthesized from RuX3(EPh3)3 (where X = Cl/Br and E = P/As) with Schiff bases in 1 : 1 molar ratio in benzene for 6 h. These complexes were characterized by elemental analysis, spectral methods (Fourier transform infrared (FT-IR), UV-Vis, 1H- and 13C-nuclear magnetic resonance (NMR) for the ligands, and electron paramagnetic resonance (EPR)), and are examined electrochemically. The complexes were efficient catalysts for oxidation of primary and secondary alcohols in their corresponding aldehydes and ketones in the presence of molecular oxygen. These complexes were also tested for their antibacterial and antifungal activities.

  DOI：

  10.1080/00958971003793241

文献信息

• Synthesis of 1,4-diazepin-5-ones under microwave irradiation and their reduction products
  作者：Nicolas Wlodarczyk、Pauline Gilleron、Régis Millet、Raymond Houssin、Jean-Pierre Hénichart

  DOI：10.1016/j.tetlet.2007.02.021

  日期：2007.4

  A new efficient access to 1,4-diazepane derivatives is described via a microwave assisted synthesis of 7-substituted-1,4-diazepin-5-ones, which proceeds rapidly in good yields. Catalytic reduction gave 1,4-diazepan-5-ones and 1,4-diazepanes whereas a ring opening was observed by hydride reduction when a phenyl group occupies the N-benzylic position. (c) 2007 Elsevier Ltd. All rights reserved.
• Preparation and properties of nickel(II) complex dyes
  作者：K. P. Balakrishnan

  DOI：10.1021/je60085a032

  日期：1980.4