1-Methoxy-pent-4-yn-2-ol | 55646-38-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Methoxy-pent-4-yn-2-ol
• 英文别名: 1-Methoxypent-4-yn-2-ol
• CAS: 55646-38-3
• 化学式: C₆H₁₀O₂
• 分子量: 114.144
• InChiKey: AHYRVNKHSDIXGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC.
  申请人：NIPPON SODA CO., LTD.

  公开号：US20160145242A1

  公开（公告）日：2016-05-26

  A medicinal active ingredient is provided which is useful for the treatment or prevention of inflammatory diseases, diseases caused by lipid oxidation, retinochoroidal disorders. A phenylimidazole derivative represented by Formula (IB) or a salt thereof is provided. A therapeutic medicine or preventive medicine is provided for inflammatory diseases, diseases caused by lipid oxidation, or retinochoroidal disorders, the medicine including at least one selected from the phenylimidazole derivative, a salt thereof, and metabolites thereof as an active ingredient. In Formula (IB), R 1a represents an alkyl group etc., R 2 represents an amino group etc., R 3 represents a halogen atom, an alkyl group etc., R 4 represents a cyano group etc., R 5 represents an alkyl group etc., and R 6 represents an alkyl group etc.

  提供了一种药用活性成分，可用于治疗或预防炎症性疾病、脂质氧化引起的疾病、视网膜脉络膜疾病。提供了一种由式（IB）所代表的苯基咪唑衍生物或其盐，该衍生物可用作治疗或预防炎症性疾病、脂质氧化引起的疾病或视网膜脉络膜疾病的治疗药物或预防药物，该药物包括至少选自苯基咪唑衍生物、其盐和其代谢物中的一种作为活性成分。在式（IB）中，R1代表烷基等，R2代表氨基等，R3代表卤素原子、烷基等，R4代表氰基等，R5代表烷基等，R6代表烷基等。