3-乙氧基环丁-1-胺盐酸盐 | 1408076-27-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 3-乙氧基环丁-1-胺盐酸盐
• 中文别名: 顺-3-乙氧基环丁-1-胺
• 英文名称: 3-Ethoxycyclobutan-1-amine hydrochloride
• 英文别名: 3-ethoxycyclobutan-1-amine;hydrochloride
• CAS: 1408076-27-6；1408076-38-9；1408074-55-4
• 化学式: C6H14ClNO
• mdl: MFCD23106133
• 分子量: 151.63
• InChiKey: IKSGSZYRXASUTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.25
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• QUINAZOLINONES AS PARP14 INHIBITORS
  申请人：Ribon Therapeutics Inc.

  公开号：US20190194174A1

  公开（公告）日：2019-06-27

  The present invention relates to quinazolinones and related compounds which are inhibitors of PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.

  本发明涉及喹唑啉酮和相关化合物，它们是PARP14的抑制剂，例如在癌症和炎症性疾病的治疗中是有用的。
• Quinazolinones as PARP14 inhibitors
  申请人：Ribon Therapeutics Inc.

  公开号：US10562891B2

  公开（公告）日：2020-02-18

  The present invention relates to quinazolinones and related compounds which are inhibitors of PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.

  本发明涉及喹唑啉酮类及相关化合物，它们是 PARP14 的抑制剂，可用于治疗癌症和炎症等疾病。
• [EN] SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS<br/>[FR] PYRAZOLOPYRIMIDINES SUBSTITUÉES EN TANT QU'INHIBITEURS D'IRAK4
  申请人：BAYER AG

  公开号：WO2021064077A1

  公开（公告）日：2021-04-08

  The present application relates to novel pyrazolopyrimidine derivatives for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments f or treatment and/or prophylaxis of diseases in humans and in animals, especially of proliferative disorder, autoimmune disorder, metabolic or inflammatory disorder characterized by an overreacting immune system, in particular rheumatological disorder, inflammatory skin disorder, cardiovascular disorder, lung disorder, kidney disorder, eye disorder, neurological disorder, pain disorder and cancer, in human as well as of allergic and/or inflammatory diseases in animals, especially of atopic dermatitis and/or Flea Allergy Dermatitis, and especially in domestic animals, particularly in dogs.