2H,2H-heptafluoro-valeryl chloride | 813-20-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 2H,2H-heptafluoro-valeryl chloride
• 英文别名: 2H,2H-Heptafluor-valerylchlorid；3,3,4,4,5,5,5-Heptafluoropentanoyl chloride；3,3,4,4,5,5,5-heptafluoropentanoyl chloride
• CAS: 813-20-7
• 化学式: C₅H₂ClF₇O
• 分子量: 246.512
• InChiKey: MEOOZXCTVDHDCE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2H,2H-heptafluoro-valeryl chloride 在 氨 、 水 作用下， 生成 2H,2H-heptafluoro-valeric acid amide
  参考文献：
  名称：

  Suicidal behavior—symptom or disorder?

  摘要：

  This article examines the diagnostic status of suicidal ideation with and without additional signs of defined or subthreshold mental disorders. Data from the World Health Organization (WHO) study on Psychological Problems in General Health Care (PPGHC) show that 8.8% of all general practice patients report that they recently had a wish to be dead. Among patients with acute depressive episodes, the rate is 34.5%, as compared with 1.3% in persons without any sign of mental disorder. Rates of suicidal ideation in persons with subthreshold disorders (10.4%) are similar to the rate in persons with other, nondepressed forms of mental disorders (12.9%). Still, 30.1% of all persons with suicidal ideation do not have a defined mental disorder, and 21.5% do not even have subthreshold disorders. But in these persons also, suicidal ideation is associated with an increased rate of depressive complaints. Suicidal ideation therefore, in any case, can be seen as an indicator of mental problems. But it seems impossible to lower the thresholds of defined mental disorders so that all forms of suicidal ideation will be covered. Instead, suicidal thoughts must be regarded as a symptom with the status of a disorder itself which should be handled as a comorbid condition if other mental disorders co-occur, Copyright (C) 2000 by W.B. Saunders Company.

  DOI：

  10.1016/s0010-440x(00)80017-6
• 作为产物：
  描述：

  甲基-(2,2,3,3,3-五氟-丙基)-胺 在 chromium(VI) oxide 、 氢氧化钾 、 氯化亚砜 、 硫酸 、 丙酮 、 二乙二醇 作用下， 生成 2H,2H-heptafluoro-valeryl chloride
  参考文献：
  名称：

  Suicidal behavior—symptom or disorder?

  摘要：

  This article examines the diagnostic status of suicidal ideation with and without additional signs of defined or subthreshold mental disorders. Data from the World Health Organization (WHO) study on Psychological Problems in General Health Care (PPGHC) show that 8.8% of all general practice patients report that they recently had a wish to be dead. Among patients with acute depressive episodes, the rate is 34.5%, as compared with 1.3% in persons without any sign of mental disorder. Rates of suicidal ideation in persons with subthreshold disorders (10.4%) are similar to the rate in persons with other, nondepressed forms of mental disorders (12.9%). Still, 30.1% of all persons with suicidal ideation do not have a defined mental disorder, and 21.5% do not even have subthreshold disorders. But in these persons also, suicidal ideation is associated with an increased rate of depressive complaints. Suicidal ideation therefore, in any case, can be seen as an indicator of mental problems. But it seems impossible to lower the thresholds of defined mental disorders so that all forms of suicidal ideation will be covered. Instead, suicidal thoughts must be regarded as a symptom with the status of a disorder itself which should be handled as a comorbid condition if other mental disorders co-occur, Copyright (C) 2000 by W.B. Saunders Company.

  DOI：

  10.1016/s0010-440x(00)80017-6

文献信息

• Fluoroalkyl surfactants
  申请人：Qiu Weiming

  公开号：US20090043130A1

  公开（公告）日：2009-02-12

  A compound of formula (I): wherein k is 1 or 2; Y is —CH 2 CH(CF 3 ) 2 or —(CH 2 ) n C F ; X is hydrogen, —(CH 2 ) n R f , or —C(O)[CF(A)] p -B—R f , wherein B is a divalent radical selected from the group consisting of a covalent bond, —O— and —(CH 2 ) m —; A is —F or —CF 3 ; and each R f is independently C 1 to C 6 perfluorinated linear or branched alkyl, optionally interrupted by one or more oxygens; R o is R o 1 or is a linear or branched alkyl having from about 10 to about 100 carbon atoms, interrupted or substituted by one or more hydrophilic groups selected from the group consisting of —O—, —OH, —NR—, —N(R) 2 , and —C(O)NR—, wherein a) the ratio of hydrophilic groups to carbon atoms is from about 1:2 to about 1:10; b) each carbon atom has at most one hydrophilic group bonded to it, and c) covalent bonding between hydrophilic groups is absent; R is hydrogen or a C 1 to C 4 linear or branched alkyl; and R o 1 is a linear or branched aliphatic group of from about 10 to about 100 carbon atoms, interrupted by about from about 5 to about 50 ether oxygens, wherein a) the ratio of ether oxygen to carbon atoms is from about 1:2 to about 1:3, b) each carbon atom has at most one ether oxygen atom bonded to it, and c) covalent bonding between ether oxygen atoms is absent; provided that 1) when Y is —(CH 2 ) n R f , R o is R o 1 ; 2) when X is hydrogen, Y is —CH 2 CH(CF 3 ) 2 ; and 3) when X is —(CH 2 ) n R f and Y is —(CH 2 ) n R f , R o is R o 1 .

  化合物式（I）：其中k为1或2；Y为—CH2CH（CF3）2或—（CH2）nCF；X为氢，—（CH2）nRf或—C（O）[CF（A）]p-B—Rf，其中B为从群组中选择的双价基团，该群组由共价键，—O—和—（CH2）m—组成；A为—F或—CF3；每个Rf独立地为C1到C6全氟线性或支链烷基，可选地由一个或多个氧原子中断；R为氢或C1到C4线性或支链烷基；Ro1为由约10到约100个碳原子组成的线性或支链烷基，由一个或多个亲水基团中断或取代，所述亲水基团从群组中选择，该群组由—O—，—OH，—NR—，—N（R）2和—C（O）NR—组成，其中a）亲水基团与碳原子的比率为约1:2至约1:10；b）每个碳原子最多只有一个与之相连的亲水基团；c）亲水基团之间的共价键缺失；Ro为Ro1或为由约10到约100个碳原子组成的线性或支链烷基，由约5到约50个醚氧原子中断，其中a）醚氧原子与碳原子的比率为约1:2至约1:3；b）每个碳原子最多只有一个与之相连的醚氧原子；c）醚氧原子之间的共价键缺失；前提是1）当Y为—（CH2）nRf时，Ro为Ro1；2）当X为氢时，Y为—CH2CH（CF3）2；3）当X为—（CH2）nRf且Y为—（CH2）nRf时，Ro为Ro1。
• Partially fluorinated compositions and surface active agents
  申请人：Acosta Erick Jose

  公开号：US20080113172A1

  公开（公告）日：2008-05-15

  Partially fluorinated amino acid derivatives are provided that are useful as organogelators and surface treatment materials to provide oil- and water-repellency properties to substrates. Also provided are composite materials comprising a porous support and a porous nanoweb. The porous nanoweb contains fibrous structures of about 10 nm to about 1000 nm effective average fiber diameter.

  提供部分氟化氨基酸衍生物，可用作有机凝胶剂和表面处理材料，以赋予基材油和水的抗性。还提供了复合材料，包括多孔支撑体和多孔纳米网。多孔纳米网包含有效平均纤维直径约为10纳米至1000纳米的纤维结构。
• FLUOROALKYL SURFACTANTS
  申请人：E. I. du Pont de Nemours and Company

  公开号：EP2173703B1

  公开（公告）日：2011-11-30
• US7638650B2
  申请人：——

  公开号：US7638650B2

  公开（公告）日：2009-12-29
• US7842626B2
  申请人：——

  公开号：US7842626B2

  公开（公告）日：2010-11-30