申请人:Bondurant Bruce
公开号:US20090304589A1
公开(公告)日:2009-12-10
The present invention relates to a radiation sensitive liposome, and the use of this liposome as carrier for therapeutic and diagnostic agent(s). In particular, the invention encompasses a liposome composition comprising a stable liposome-forming lipid and a polymerizable colipid, and a chain transfer agent. The present invention further contemplates methods of diagnosing and treating conditions and diseases that are responsive to liposome-encapsulated or associated agents.
本发明涉及一种辐射敏感的脂质体,以及将该脂质体用作治疗和诊断药物的载体。特别地,本发明涵盖了一种脂质体组合物,包括稳定的脂质体形成脂质和可聚合的共脂质以及链转移剂。本发明还涵盖了利用脂质体封装或关联的药物诊断和治疗对脂质体敏感的疾病和病症的方法。