lactose | 207570-54-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: lactose
• 英文别名: D-galacto-hexopyranosyl D-gluco-hexopyranoside；(2R,3S,4S,5R)-2-(hydroxymethyl)-6-[(3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol
• CAS: 207570-54-5
• 化学式: C₁₂H₂₂O₁₁
• 分子量: 342.3
• InChiKey: HDTRYLNUVZCQOY-IXKFSGTESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  190
• 氢给体数：
  8
• 氢受体数：
  11

文献信息

• Method of Preparing A Glycoside Of A Mono- Or Diacylglycerol Product From A Plant Material
  申请人：BAGGER Christian Lorentz

  公开号：US20120184023A1

  公开（公告）日：2012-07-19

  The present invention provides a method of preparing a glycoside of a mono- or diacylglycerol product from a plant material. The method comprises the steps of: (i) optionally milling the plant material, (ii) extracting the optionally milled plant material with a first aqueous extraction solution obtaining a first liquid phase and a first solid phase, (iii) separating the liquid phase from the solid phase to obtain a glycoside of mono- or diacylglycerol product, (iv) extracting the solid phase from step (iii) with a second extraction solution obtaining a second liquid phase and a second phase, and (v) separating the second liquid phase from the second solid phase to obtain a second and a third glycoside of mono- or diacylglycerol product, wherein the second extraction solution further comprises a cell wall degrading enzyme or a mixture of cell wall degrading enzymes.

  本发明提供了一种从植物材料制备单酰基或双酰基甘油产物的糖苷的方法。该方法包括以下步骤：(i) 可选研磨植物材料，(ii) 用第一种水性提取溶液提取可选研磨的植物材料，得到第一液相和第一固相，(iii) 将液相与固相分离，得到单酰基或双酰基甘油产物的糖苷，(iv) 用第二种提取溶液提取步骤(iii)中的固相，得到第二液相和第二相，(v) 将第二液相与第二固相分离，得到第二和第三种单酰基或双酰基甘油产物的糖苷，其中，第二种提取溶液还包括细胞壁降解酶或细胞壁降解酶混合物。
• Method of Preparing a Glycoside of a Mono or Diacylglycerol Product From a Plant Material
  申请人：Bagger Christian Lorentz

  公开号：US20090209746A1

  公开（公告）日：2009-08-20

  The present invention provides a method of preparing a glycoside of a mono- or diacylglycerol product from a plant material. The method comprises the steps of: (i) optionally milling the plant material, (ii) extracting the optionally milled plant material with a first aqueous extraction solution obtaining a first liquid phase and a first solid phase, (iii) separating the liquid phase from the solid phase to obtain a glycoside of mono- or diacylglycerol product, (iv) extracting the solid phase from step (iii) with a second extraction solution obtaining a second liquid phase and a second phase, and (v) separating the second liquid phase from the second solid phase to obtain a second and a third glycoside of mono- or diacylglycerol product, wherein the second extraction solution further comprises a cell wall degrading enzyme or a mixture of cell wall degrading enzymes.

  本发明提供了一种从植物材料制备单酰基或二酰基甘油产物的糖苷的方法。该方法包括以下步骤：（i）可选地研磨植物材料，（ii）用第一水提取溶液提取可选研磨的植物材料，得到第一液相和第一固相，（iii）将液相与固相分离，以得到单酰基或二酰基甘油产物的糖苷，（iv）用第二提取溶液提取步骤（iii）中的固相，得到第二液相和第二相，（v）将第二液相与第二固相分离，以得到第二和第三单酰基或二酰基甘油产物的糖苷，其中第二提取溶液还包括细胞壁降解酶或细胞壁降解酶混合物。
• Trehalose phosphorylase, its preparation and uses
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0841397A2

  公开（公告）日：1998-05-13

  A thermostable trehalose phosphorylase which is obtainable from microorganisms of the genus Thermoanaerobium and which hydrolyzes trehalose in the presence of an inorganic phosphoric acid to form D-glucose and β-D-glucose-1-phosphoric acid. The trehalose phosphorylase can be also prepared by recombinant DNA technology. When the enzyme is allowed to contact with β-D-glucose-1-phosphoric acid as a saccharide donor in the presence of other saccharides, glucosyl-transferred saccharides including glucosyl-D-galactoside, which are conventionally known but scarcely obtainable, can be produced on an industrial-scale and in a relatively-low cost.

  一种可从热花生菌属微生物中获得的热稳定性脱卤糖磷酸化酶，它能在无机磷酸存在下水解脱卤糖，生成 D-葡萄糖和 β-D-葡萄糖-1-磷酸。也可以通过 DNA 重组技术制备妥尔糖磷酸化酶。在有其他糖类存在的情况下，让酶与β-D-葡萄糖-1-磷酸作为糖类供体接触，就能以相对较低的成本在工业规模上生产出葡萄糖基转移的糖类，包括葡萄糖基-D-半乳糖苷。
• METHOD OF INHIBITING WATER CONTENT VARIATION OF COMPOSITION AND USE THEREOF
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP1582105A1

  公开（公告）日：2005-10-05

  The present invention has objects for providing a method for inhibiting the moisture variation in compositions, a composition whose moisture variation is inhibited, and an agent for inhibiting the moisture variation in compositions. The objects are solved by providing a method for inhibiting the moisture variation in compositions comprising incorporating into a composition a saccharide-derivative(s) of α,α-trehalose as an effective ingredient, a composition whose moisture variation is inhibited by incorporating the saccharide-derivative(s), a moisture variation inhibiting agent containing the saccharide-derivative(s) as an effective ingredient, and uses thereof.

  本发明的目的是提供一种抑制组合物湿度变化的方法、一种湿度变化受到抑制的组合物以及一种抑制组合物湿度变化的制剂。本发明的目的是通过提供一种抑制组合物湿度变化的方法来实现的，该方法包括在组合物中加入作为有效成分的α,α-曲哈糖的糖衍生物、通过加入糖衍生物而抑制湿度变化的组合物、含有作为有效成分的糖衍生物的湿度变化抑制剂及其用途。
• SKIN PREPARATION FOR EXTERNAL USE CHARACTERIZED BY CONTAINING SUGAR DERIVATIVE OF a,a-TREHALOSE
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP1600143A1

  公开（公告）日：2005-11-30

  The present invention has an object to provide an external dermatological formulation having satisfactory blood flow-promoting effect, antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing effect, hair nourishing effect, emusifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and/or transdermal absorption-promoting effect with a satisfactory safety and skin feeling; The object is solved by providing an external dermatological formulation comprising a saccharide derivative of α,α-trehalose and one or more members selected from substances having any one of blood flow-promoting effect , antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing efect, hair nourishing effect, emulsifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and transdermal absorption-promoting effect.

  本发明的目的是提供一种具有令人满意的促进血液流动效果、抗炎效果、抗菌效果、保湿效果、美白效果、紫外线吸收效果、紫外线散射效果、抗氧化效果、生发效果、养发效果、润肤效果、收敛效果、减少皱纹效果、细胞激活效果和/或透皮吸收促进效果，并具有令人满意的安全性和肤感的皮肤外用制剂；本发明的目的是通过提供一种外用皮肤病配方来实现的，该配方包含 α,α-三卤糖的糖衍生物和一种或多种选自具有促进血流效果、抗炎效果、抗菌效果、保湿效果、美白效果、抗菌效果、保湿效果、美白效果中任一种效果的物质、保湿效果、美白效果、紫外线吸收效果、紫外线散射效果、抗氧化效果、生发效果、养发效果、乳化效果、收敛效果、除皱效果、细胞活化效果和透皮吸收促进效果中的任一种。