benzyl 2,3-di-O-benzyl-4,6-di-O-tosyl-β-D-glucopyranose | 190435-70-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: benzyl 2,3-di-O-benzyl-4,6-di-O-tosyl-β-D-glucopyranose
• CAS: 190435-70-2
• 化学式: C₄₁H₄₂O₁₀S₂
• 分子量: 758.91
• InChiKey: TTXVDLQVKHOXKK-PGSFLWIGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  53.0
• 可旋转键数：
  16.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  123.66
• 氢给体数：
  0.0
• 氢受体数：
  10.0

反应信息

• 作为反应物：
  描述：

  甲胺 、 benzyl 2,3-di-O-benzyl-4,6-di-O-tosyl-β-D-glucopyranose 以 乙醇 为溶剂， 反应 4.0h， 生成 benzyl 2,3-di-O-benzyl-4,6-dideoxy-4,6-methylimino-β-D-galactopyranose
  参考文献：
  名称：

  Synthesis of monosaccharide-fused azetidines

  摘要：

  Primary amines reacted upon 4,6-ditosylates of glucopyranosides to give an azetidine ring fused on C-4 and C-6 of the pyranose ring. On the other hand, the 4,6-ditosylate of benzyl mannopyranoside led to the 4,6-diamino-4,6-dideoxy derivative in a good yield. All the compounds and their precursors were identified by H-1 and C-13 NMR spectroscopy. Assignments of proton signals were made unambiguously using homodecoupling experiments. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00015-3
• 作为产物：
  描述：

  D-葡萄糖 以 吡啶 为溶剂， 反应 72.0h， 生成 benzyl 2,3-di-O-benzyl-4,6-di-O-tosyl-β-D-glucopyranose
  参考文献：
  名称：

  Synthesis of monosaccharide-fused azetidines

  摘要：

  Primary amines reacted upon 4,6-ditosylates of glucopyranosides to give an azetidine ring fused on C-4 and C-6 of the pyranose ring. On the other hand, the 4,6-ditosylate of benzyl mannopyranoside led to the 4,6-diamino-4,6-dideoxy derivative in a good yield. All the compounds and their precursors were identified by H-1 and C-13 NMR spectroscopy. Assignments of proton signals were made unambiguously using homodecoupling experiments. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00015-3