2-[2-[[4,6-bis[2-(1H-indol-3-yl)ethylamino]-1,3,5-triazin-2-yl]amino]ethyl]guanidine | 1334432-05-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-[2-[[4,6-bis[2-(1H-indol-3-yl)ethylamino]-1,3,5-triazin-2-yl]amino]ethyl]guanidine
• CAS: 1334432-05-1
• 化学式: C₂₆H₃₁N₁₁
• 分子量: 497.606
• InChiKey: AUXBOKKVZKSUAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  37
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  171
• 氢给体数：
  7
• 氢受体数：
  7

文献信息

• s-TRIAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME
  申请人：KALLENBACH Neville Robert

  公开号：US20110230489A1

  公开（公告）日：2011-09-22

  Novel s-triazine compounds are disclosed that have a formula represented by the following: L 1 , L 2 , L 3 , R 1 , R 2 , R 3 , R 4 , R 5a , R 5b , and R 5c are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, where microbial infection is either a direct cause or a related condition.

  揭示了具有以下表示式的新型s-三嗪化合物：L1、L2、L3、R1、R2、R3、R4、R5a、R5b和R5c。这些化合物可以制备为药物组合物，并可用于哺乳动物，包括人类，的预防和治疗多种疾病，其中微生物感染是直接原因或相关病症。
• US8796449B2
  申请人：——

  公开号：US8796449B2

  公开（公告）日：2014-08-05
• US9273015B2
  申请人：——

  公开号：US9273015B2

  公开（公告）日：2016-03-01
• [EN] S-TRIAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME<br/>[FR] COMPOSÉS DE S-TRIAZINE, COMPOSITIONS PHARMACEUTIQUES ET PROCÉDÉS D'UTILISATION ASSOCIÉS
  申请人：UNIV NEW YORK

  公开号：WO2011115677A1

  公开（公告）日：2011-09-22

  Novel s-triazine compounds are disclosed that have a formula represented by the following: L1, L2, L3, R1, R2, R3, R4, R5a, R5b, and R5c are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, where microbial infection is either a direct cause or a related condition.