1,4-Dihydroxy-3,3-dimethyl-butan-2-one | 42328-10-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,4-Dihydroxy-3,3-dimethyl-butan-2-one
• 英文别名: 1,4-Dihydroxy-3,3-dimethylbutan-2-one
• CAS: 42328-10-9
• 化学式: C₆H₁₂O₃
• 分子量: 132.159
• InChiKey: VCLSUNMNDIKRMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• LXR MODULATORS
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20160289222A1

  公开（公告）日：2016-10-06

  The present invention provides compounds of Formula I and Formula II: or pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXRs), and compositions comprising any of such novel compounds and methods of use thereof. These compounds are useful as medicaments for treatment and/or prophylaxis for diseases or conditions related to activity of LXRs.
• US9751869B2
  申请人：——

  公开号：US9751869B2

  公开（公告）日：2017-09-05