硬脂酸2-[(1-十八烷酰基)氨基]乙脂 | 14351-40-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 硬脂酸2-[(1-十八烷酰基)氨基]乙脂
• 中文别名: 乙醇胺N,O-二硬脂酸酯；硬脂酰胺MEA-硬脂酸酯
• 英文名称: stearic acid monoethanolamide stearate
• 英文别名: 2-stearamidoethyl stearate；distearoylethanoylamine；DSEA；2-[(1-oxooctadecyl)amino]ethyl stearate；octadecanoic acid, 2-((1-oxooctadecyl)amino)ethyl ester；2-Stearamidoethylstearat；Stearic monoethanolamide stearate；2-(octadecanoylamino)ethyl octadecanoate
• CAS: 14351-40-7
• 化学式: C₃₈H₇₅NO₃
• 分子量: 594.018
• InChiKey: ZAYHEMRDHPVMSC-UHFFFAOYSA-N

物化性质

• 熔点：
  92-94 °C(Solv: ethanol (64-17-5))
• 沸点：
  678.4±38.0 °C(Predicted)
• 密度：
  0.892±0.06 g/cm3(Predicted)
• LogP：
  15.665 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  16.3
• 重原子数：
  42
• 可旋转键数：
  36
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  55.4
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2924199090

SDS

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Section 1. Chemical Product and Company Identification
Stearoyl Monoethanolamide Stearate
Common Name/
Trade Name
Stearoyl Monoethanolamide Stearate

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Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
Eye Contact
15 minutes. Get medical attention if irritation occurs.
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Skin Contact
Serious Skin Contact Not available.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Not available.
Serious Inhalation
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Not available.
Serious Ingestion

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Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Not available.
Flash Points
Not available.
Flammable Limits
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards in
Risks of explosion of the product in presence of static discharge: Not available.
Presence of Various
Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
Not available.
Special Remarks on
Fire Hazards
Not available.
Special Remarks on
Explosion Hazards

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Section 6. Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading
Small Spill
water on the contaminated surface and dispose of according to local and regional authority requirements.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on
Large Spill
the contaminated surface and allow to evacuate through the sanitary system.
Stearoyl Monoethanolamide Stearate

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Section 7. Handling and Storage
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
Precautions
breathe dust. Keep away from incompatibles such as oxidizing agents.
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Storage

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Section 8. Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
Engineering Controls
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to
avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
of a Large Spill
handling this product.
Exposure Limits Not available.

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Section 9. Physical and Chemical Properties
Solid. (Powdered solid. Crystalline powder.) Not available.
Physical state and O dor
appearance
Not available.
Taste
594.02 g/mole
Molecular Weight
White to yellowish.
Color
Not applicable.
pH (1% soln/water)
Not available.
Boiling Point
84°C (183.2°F) - 86 C.(186.8 F.)
Melting Point
Not available.
Critical Temperature
Not available.
Specific Gravity
Not applicable.
Vapor Pressure
Not available.
Vapor Density
Not available.
Volatility
Not available.
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Not available.
Ionicity (in Water)
Not available.
Dispersion Properties
Insoluble in cold water, hot water.
Solubility

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Section 10. Stability and Reactivity Data
The product is stable.
Stability
Not available.
Instability Temperature
Conditions of Instability Excess heat, incompatible materials, sunlight
Incompatibility with various Reactive with oxidizing agents.
substances
Not available.
Corrosivity
Stearoyl Monoethanolamide Stearate
Protect from light.
Special Remarks on
Reactivity
Not available.
Special Remarks on
Corrosivity
Will not occur.
Polymerization

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Section 11. Toxicological Information
Inhalation. Ingestion.
Routes of Entry
Toxicity to Animals LD50: Not available.
LC50: Not available.
Chronic Effects on Humans Not available.
Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Other Toxic Effects on
Humans
Not available.
Special Remarks on
Toxicity to Animals
Not available.
Special Remarks on
Chronic Effects on Humans
Acute Potential Health Effects:
Special Remarks on other
Skin: May cause skin irritation.
Toxic Effects on Humans
Eyes: May cause eye irritation.
Inhalation: May cause respiratory tract irritation.
Ingestion: May be harmful if swallowed.

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Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
The product itself and its products of degradation are not toxic.
Toxicity of the Products
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation

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Section 13. Disposal Considerations
Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental control
regulations.

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Section 14. Transport Information
Not a DOT controlled material (United States).
DO T Cl assi fi cati on
Not applicable.
Identification
Not applicable.
Special Provisions for
Transport
Stearoyl Monoethanolamide Stearate
DO T (Pi ctograms)

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Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
California prop. 65: This product contains the following ingredients for which the State of California has found to
California
cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause birth defects which would require a warning under the statute: No products were found.
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No.
Other Regulations
238-310-5).
Canada: Listed on Canadian Domestic Substance List (DSL).
China: Listed on National Inventory.
Japan: Listed on National Inventory (ENCS).
Korea: Not listed on National Inventory (KECI).
Philippines: Not listed on National Inventory (PICCS).
Australia: Listed on AICS.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC) This product is not classified according Not applicable.
to the EU regulations.
Health Hazard
HMIS (U.S.A.) 1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity 0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG(Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Stearoyl Monoethanolamide Stearate
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or equivalent.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  硬脂酸2-[(1-十八烷酰基)氨基]乙脂 在 正丁胺 、 苯基磷二酰胺 作用下， 生成 4,5-二氢-2-十七烷基-1H-咪唑
  参考文献：
  名称：

  Butler, Richard N.; Thornton, John D.; O'Regan, C.B., Journal of the Chemical Society. Perkin transactions I, 1983, p. 2197 - 2200

  摘要：

  DOI：
• 作为产物：
  描述：

  硬脂酰胺MEA 以 水 为溶剂， 生成 硬脂酸2-[(1-十八烷酰基)氨基]乙脂
  参考文献：
  名称：

  Butler,R.N. et al., Journal of the Chemical Society. Perkin transactions I, 1978, p. 373 - 377

  摘要：

  DOI：

文献信息

• [EN] PERSONAL CARE COMPOSITIONS CONTAINING CERTAIN CYCLIC SILOXANES<br/>[FR] COMPOSITIONS DE SOINS PERSONNELS CONTENANT CERTAINS SILOXANES CYCLIQUES
  申请人：DOW CORNING

  公开号：WO2011066359A1

  公开（公告）日：2011-06-03

  Personal care compositions containing certain cyclic siloxanes are disclosed. The cyclic siloxanes are prepared by reacting a chloro endblocked polydimethylsiloxane with a diol functional compound containing at least 2 carbon atoms.

  本发明涉及含有特定环状硅氧烷的个人护理组合物。所述环状硅氧烷是通过将氯端封闭的聚二甲基硅氧烷与至少含有2个碳原子的二元醇官能化合物反应制备而成。
• Pharmaceuticals and Surfactants from Alga-Derived Feedstock: Amidation of Fatty Acids and Their Derivatives with Amino Alcohols
  作者：Anastasia Tkacheva、Inkar Dosmagambetova、Yann Chapellier、Päivi Mäki-Arvela、Imane Hachemi、Risto Savela、Reko Leino、Carolina Viegas、Narendra Kumar、Kari Eränen、Jarl Hemming、Annika Smeds、Dmitry Yu. Murzin

  DOI：10.1002/cssc.201500526

  日期：2015.8.24

  mildly acidic H‐MCM‐41 at 70 % conversion in 3 h at 180 °C. Highly acidic catalysts favored the formation of the ester amine, whereas the amide was obtained with a catalyst that exhibited an optimum acidity. The conversion levels achieved with different fatty acids in the range C12–C18 were similar; this shows that the fatty acid length does not affect the amidation rate. The amidation of methyl palmitate

  酰胺化可再生原料，例如脂肪酸，酯和小球藻以沸石和介孔材料为催化剂和乙醇胺，丙氨醇和亮氨醇证明了基于藻类的生物柴油。后两个可以源自藻类中存在的氨基酸。如NMR和IR光谱所证实的，主要产物是脂肪链烷醇酰胺和相应的酯胺。不可忽略的是在180°C下用乙醇胺对工业级油酸和硬脂酸进行热酰胺化。两者均带来61％的转化率。在硬脂酸与乙醇胺的酰胺化反应中，3小时后H-Beta-150的转化率为80％，而油酸的转化率仅为63％。这表明微孔催化剂不适合该酸，并显示起皱的构象。在180°C下3小时内，中等酸性的H-MCM-41在70％的转化率下，对硬脂酰乙醇酰胺的最高选择性为92％。高酸性催化剂有利于酯胺的形成，而酰胺是用表现出最佳酸度的催化剂获得的。在C12–C18范围内，使用不同的脂肪酸可获得的转化率相近。这表明脂肪酸长度不影响酰胺化速率。棕榈酸甲酯和生物柴油的酰胺化反应在酸性催化剂上的转化率较低，这表明酯酰胺化反应的反应机理是不同的。
• Shampoo containing a gel network
  申请人：The Procter & Gamble Company

  公开号：US20030223952A1

  公开（公告）日：2003-12-04

  The compositions of the present invention relate to improved shampoo compositions having from about from about 5 to about 50 weight percent of a detersive surfactant, at least about 0.05 weight percent of a fatty alcohol gel network and at least about 20.0 weight percent of an aqueous carrier.

  本发明的组合物涉及改进的洗发水组合物，其含有约5至50重量％的去污表面活性剂，至少约0.05重量％的脂肪醇凝胶网络和至少约20.0重量％的水基载体。
• Amide esters as hydrocarbon gellants
  申请人：O'Lenick A. Kevin

  公开号：US20060286061A1

  公开（公告）日：2006-12-21

  The invention relates to gelling agents, and in particular to gellants for low polarity liquids such as hydrocarbons, and the use thereof in commercial products, e.g., personal care products.

  本发明涉及凝胶剂，特别是用于低极性液体（如烃类）的凝胶剂，以及其在商业产品（例如个人护理产品）中的应用。
• Silicone-Organic Hybrid Emulsions In Personal Care Applications
  申请人：Canfield Lylenette

  公开号：US20110150818A1

  公开（公告）日：2011-06-23

  Personal care compositions containing silicone polymer and organic polymer containing alloy and/or hybrid emulsions are disclosed. The silicone organic hybrid emulsions are particularly useful in hair care formulations to simultaneously provide conditioning and styling benefits. The silicone organic hybrid emulsions are also useful in color cosmetic formulations to provide shine and wash-off resistance benefits.

  本发明涉及含有硅聚合物和有机聚合物的合金和/或混合乳液的个人护理组合物。硅有机混合乳液在发护配方中特别有用，可以同时提供调理和造型效果。硅有机混合乳液还可用于彩妆配方中，以提供光泽和抗洗效果。