TMS a-glucoside | 1372605-74-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: TMS a-glucoside
• 英文别名: TMS b-glucoside；(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-trimethylsilyloxyoxane-3,4,5-triol
• CAS: 1372605-74-7
• 化学式: C₉H₂₀O₆Si
• 分子量: 252.34
• InChiKey: HCWAILZFCRLWPS-ZEBDFXRSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.36
• 重原子数：
  16.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.38
• 氢给体数：
  4.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  甲基-Alpha-D-吡喃葡糖苷 、 N,O-双(三甲基硅烷基)三氟乙酰胺 以 甲醇 、 水 为溶剂， 反应 3.0h， 生成 TMS-alpha-D-(+)-Glucose 、 TMS a-glucoside
  参考文献：
  名称：

  Lipid metabolites with free-radical scavenging activity from Euphorbia helioscopia L.

  摘要：

  The methanolic extract of the plant Euphorbia helioscopia L. exhibited an interesting free-radical scavenging activity. From the aerial parts of Euphorbia helioscopia L. (Euphorbiaceae), a complex mixture of seven cerebrosides together with glucoclionasterol, a digalactosyldiacylglycerol and a diacylmonogalactosylglycerol were identified. The structures of the cerebrosides were characterized as 1-O-β-D-glucosides of phytosphingosines, which comprised (2S, 3S, 4E, 8E)-2-amino-4(E),8(E)-octadecadiene-1,3-diol, (2S, 3S, 4E, 8Z)-2-amino-4(E),8(Z)-octadecadiene-1,3-diol, (2S, 3S, 4R, 8Z)-2-amino-8(Z)-octadecene-1,3,4-triol as long chain bases with seven 2-hydroxy fatty acids of varying chain lengths (C16, C24:1, C26:1, C24, C26, C28:1) linked to the amino group. The glycosylglycerides were characterized as (2S)-2,3-O-di-(9,12,15-octadecatrienoyl)-glyceryl-6-O-(α-D-galactopyranosyl)-β-D-galactopyranoside and (2S)-2,3-O-di-(9,12,15-octadecatrienoyl)-glyceryl-1-O-β-D-galactopyranoside. The structures were established on the basis of spectroscopic data and chemical reactions.

  DOI：

  10.1016/j.chemphyslip.2014.03.001