(2S,3R,4R,5S,6R)-2-(3-chroman-6-ylmethyl-4-cyclopropyl-phenyl)-6-methylsulfanyltetrahydropyran-3,4,5-triol | 1402348-21-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4R,5S,6R)-2-(3-chroman-6-ylmethyl-4-cyclopropyl-phenyl)-6-methylsulfanyltetrahydropyran-3,4,5-triol
• 英文别名: (2S,3R,4R,5S,6R)-2-[4-cyclopropyl-3-(3,4-dihydro-2H-chromen-6-ylmethyl)phenyl]-6-methylsulfanyloxane-3,4,5-triol
• CAS: 1402348-21-3
• 化学式: C₂₅H₃₀O₅S
• 分子量: 442.576
• InChiKey: VEDPAGZYFBVLCR-WJGLBBAVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• GLYCOSIDE DERIVATIVES AND USES THEREOF
  申请人：Bebernitz Gregory Raymond

  公开号：US20130203975A1

  公开（公告）日：2013-08-08

  The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

  本发明提供了一种I式化合物；一种制造本发明化合物的方法，以及其治疗用途。本发明还提供了一种药理活性剂的组合和制药组合物。
• SULFONYLUREA MODULATORS OF ENDOTHELIN RECEPTOR
  申请人：Rao Tadimeti

  公开号：US20110082151A1

  公开（公告）日：2011-04-07

  The present invention relates to new sulfonylurea modulators of endothelin receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
• US8722633B2
  申请人：——

  公开号：US8722633B2

  公开（公告）日：2014-05-13
• [EN] GLYCOSIDE DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS DE GLYCOSIDE ET LEURS UTILISATIONS
  申请人：NOVARTIS AG

  公开号：WO2012140596A1

  公开（公告）日：2012-10-18

  The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.